… Though a statistically significant difference in the primary … could only be found on the company
website and in press releases… C3 glomerulonephritis (C3GN) and dense deposit disease (…

… The primary objective of the current study was to identify … Focal granular IgM deposits were
found along segments of the … with pathogenic variants in complement genes (ie, C3, n=3, and …

… is a common form of primary glomerulonephritis for which … that the IgA isolated from the
mesangial deposits in IgAN is … The origin of mesangial C3 deposits in IgAN has not been …

… ) is the most common primary glomerulonephritis in the world. A … IgAN is a single pathogenic
entity. Stratification of patients on … C3 deposits may help differentiate IgAN from isolated …

… The most common site of infection was skin in peri- (23 of 97, … blockers were significant risk
factors for progression to kidney … Patients with isolated C3 deposits as compared with patients …

… most prevalent form of primary glomerulonephritis, has growing … staining may colocalize with
C3 deposits and correlate with … may be affected by genetic predisposition, which influences …

… either be idiopathic/primary or-much more … C3 deposits is referred to as C3 glomerulopathy
(C3G). C3G is further divided into C3 glomerulonephritis (C3GN) and dense deposit disease (…

… including atypical hemolytic uremic syndrome (aHUS), C3 … microscopy examination suggests
dense deposit disease (DDD). … labeled primary aHUS. Recent work has highlighted that …

… common primary glomerular diseases such as IgA nephropathy, membranous glomerulonephritis
(MGN), and diabetic kidney disease (… C3 deposits, and the 2 common entities that are …

… IgAN is the most common primary glomerular disease, … Properdin is co-deposited with IgA
and C3 in 75%–100% of … activation, like in atypical haemolytic uremic syndrome (aHUS), but …