… No significant toxicity difference was observed in cells exposed to either fresh or 60 day-…
the further stages of promotion or progression. Moreover, adequate epidemiological information …

… , 38 were in vitro approaches and 21 in vivo studies. Thirteen … nanoparticles of 50 nm,
suggesting that TiO 2 -NPs toxicity in … heterogenous results on the development effects due to the …

… the latest research progress of related genotoxic effects through in vivo studies and in vitro
cell tests… The mechanism of TiO 2 NPs-induced toxicity may be related to its stronger oxidative …

… A review of in vivo pulmonary and oral toxicity studies - Revised 11-6… Human in vivo and in
vitro studies on gastrointestinal … crypt development in the rat colon. Sci Rep 2017; 7: 40373. …

… The previous in vitro and in vivo tests confirm the toxic effects of … into systemic circulation in
rats and humans [51,52,53]. … 2 NPs had an effect on the development of Parkinson’s disease (…

… Thus, chronic toxic effects cannot be evaluated in this study. Second, some physicochemical
characteristics of TiO 2 -NPs or experimental protocols, such as sonication, aggregation …

… -the-art, is that in vivo models have not been good enough and at … and Development (OECD)
methodology for acute toxicity … observed, systemically, in this study underlines the very low …

… and other fields as the rapid development of nanotechnology [1, 2]… cornea damage, but also
resulted in potentially systemic … However, research on toxicity of TiO 2 NPs has not kept pace …

… This study aimed to evaluate whether oxidative stress is one of the toxicity mechanisms induced
by nano-titanium dioxide … With the development of nanotechnology, nanomaterials have …

… We included information from in vivo studies using advanced … kinetic studies, others are
general toxicity studies or studies … The same holds for systematic research on the relationships …