Influence of polychlorinated biphenyls and organochlorine pesticides on the inflammatory milieu. A systematic review of in vitro, in vivo and epidemiological studies

FM Peinado, F Artacho-Cordón… - Environmental …, 2020 - Elsevier
PCBs and OCPs and the development of a pro-inflammatory milieu, with only few discrepancies.
However, given the limited epidemiological evidence … In this regard, coplanar PCBs are …

PCB 126 induces monocyte/macrophage polarization and inflammation through AhR and NF-κB pathways

C Wang, MC Petriello, B Zhu, B Hennig - Toxicology and applied …, 2019 - Elsevier
… In the present study, we provide evidence that coplanar PCBs (PCB 126) can induce or …
, a recent study showed that PCB 126 activates a vigorous pro-inflammatory state in fat cell …

Evaluation of Early Biomarkers of Atherosclerosis Associated with Polychlorinated Biphenyl Exposure: An in Vitro and in Vivo Study

B Yang, Z Ye, Y Wang, H Guo… - Environmental …, 2022 - ehp.niehs.nih.gov
Polychlorinated biphenyls (PCBs) are typical environmental pollutants that have been
widely used in industry in the last century. Approximately 1.5 to 2.5 million 2.5 million tons of …

[HTML][HTML] A systematic evidence map for the evaluation of noncancer health effects and exposures to polychlorinated biphenyl mixtures

LM Carlson, K Christensen, SK Sagiv, P Rajan… - Environmental …, 2023 - Elsevier
… effects from exposure to PCBs has not been systematically … into a systematic evidence map
of PCB exposure and noncancer … an evidence map for noncancer health endpoints and PCB

The bladder is a novel target of developmental polychlorinated biphenyl exposure linked to increased inflammatory cells in the bladder of young mice

CL Kennedy, A Spiegelhoff, K Wang, T Lavery… - Toxics, 2021 - mdpi.com
… , PCBs have been shown to alter proinflammatory and … To expand upon the evidence that
PCBs can increase serum … , we sought to determine whether PCBs alter inflammation in other …

PCB cause global DNA hypomethylation of human peripheral blood monocytes in vitro

MS Vidali, S Dailianis, D Vlastos… - Environmental Toxicology …, 2021 - Elsevier
… between exposure to polychlorinated biphenyls (PCB) and … of healthy volunteers and
provided evidence in support of an … of PCB and was more potent for the dioxin-like coplanar PCB-…

Effects of PCB126 on Adipose-to-Muscle Communication in an in Vitro Model

A Caron, F Ahmed, V Peshdary… - Environmental …, 2020 - ehp.niehs.nih.gov
… body of evidence supporting the role of coplanar PCBs in the … sensitivity and PCB126 on
pro-inflammatory cytokines, but how … human adipocytes), in the concentration of coplanar PCB

ROS-induced NLRP3 inflammasome priming and activation mediate PCB 118-induced pyroptosis in endothelial cells

Y Long, X Liu, X Tan, C Jiang, S Chen, G Liang… - Ecotoxicology and …, 2020 - Elsevier
evidence from in vivo and in vitro studies has shown that exposure to PCBs, such as PCB77,
PCB104, PCB … ,5-pentachlorobiphenyl (PCB 118), a member of the coplanar PCBs, disturbs …

Exposure to the Dioxin-like Pollutant PCB 126 Afflicts Coronary Endothelial Cells via Increasing 4-Hydroxy-2 Nonenal: A Role for Aldehyde Dehydrogenase 2

B Roy, Z Yang, G Pan, K Roth, M Agarwal, R Sharma… - Toxics, 2022 - mdpi.com
… increased levels of plasma proinflammatory cytokines, increased … These dioxin-like PCBs
have a coplanar structure, leading to … Experimental evidence has further highlighted the …

A critical review of polychlorinated biphenyls metabolism, metabolites, and their correlation with oxidative stress

J Liu, Y Tan, E Song, Y Song - Chemical Research in Toxicology, 2020 - ACS Publications
… Oxidative stresses play an important role in the toxic action of PCBs. Dioxin-like, coplanar
PCBs have … , there is no evidence for higher chlorinated PCBs (>6) undergoing hydroxylation. …