[HTML][HTML] Predicting consequences of POP-induced disruption of blubber glucose uptake, mass gain rate and thyroid hormone levels for weaning mass in grey seal …

KA Bennett, KJ Robinson, HC Armstrong… - Environment …, 2021 - Elsevier
… DL-PCBs partially overcame the effect of DL-PCB -mediated reduction in blubber glucose
uptake. Overall, DL-PCBs … At the organismal level, in vivo rodent studies also provide evidence

Environmental Chemical Obesogens

D Teixeira, D Pestana - … Obesity: From its Causes to impact on …, 2020 - books.google.com
… Undeniably, there is abundant evidence from epidemiological, in vitro and in vivo studies …
Proinflammatory properties of coplanar PCBs: in vitro and in vivo evidence. Toxicol Appl …

Intrarenal 1-methoxypyrene, an aryl hydrocarbon receptor agonist, mediates progressive tubulointerstitial fibrosis in mice

G Cao, H Miao, Y Wang, D Chen, X Wu… - Acta Pharmacologica …, 2022 - nature.com
… The latest evidence has shown that MMT also affects ECM in TIF [15, 16]. … coplanar
polychlorinated biphenyls, such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) [21]. Recent …

Exposure to pollutants altered glucocorticoid signaling and clock gene expression in female mice. Evidence of tissue-and sex-specificity

N Vega, C Pinteur, G Buffelan, E Loizon, H Vidal… - Chemosphere, 2021 - Elsevier
… Today, the production of PCBs is banned and … the coplanar PCBs) was below the tolerable
daily intake (TDI) dose but it was up to 80 ng/kg body weight per day for non-coplanar PCBs

Dioxin and related compound detection: Perspectives for optical monitoring

B Patrizi, M Siciliani de Cumis, S Viciani… - International Journal of …, 2019 - mdpi.com
… mono-ortho PCBs have coplanar structures that make them more toxic since they bind with
higher affinity the AhR receptor. For this reason non-ortho and mono-ortho PCBs have been …

Immunotoxicity of xenobiotics in fish: a role for the aryl hydrocarbon receptor (AhR)?

H Segner, C Bailey, C Tafalla, J Bo - International journal of molecular …, 2021 - mdpi.com
… the expression of pro-inflammatory cytokines as well as ROS … Evidence that the AhR
pathway is functional comes from the … the fish immune response to coplanar PCBs is age-dependent…

Prenatal environmental exposure to persistent organic pollutants and indices of overweight and cardiovascular risk in Dutch adolescents

SA Berghuis, AF Bos, PJJ Sauer, G Bocca - Nutrients, 2022 - mdpi.com
… For PCBs and PBDEs, there was no conclusive evidence that … Higher PCB exposure was
associated with increasing weight in … differentiation and pro-inflammatory adipokine expression. …

Overview of biological mechanisms of human carcinogens

N Birkett, M Al-Zoughool, M Bird, RA Baan… - Journal of Toxicology …, 2019 - Taylor & Francis
… human, experimental and mechanistic evidence on agents suspected of inducing cancer
in humans, using a well-established weight of evidence approach. The monographs provide …

Endocrine disruptors in the pathogenesis of metabolic syndrome

UK Saikia, A Kumar - Metabolic Syndrome, 2024 - Elsevier
… signaling pathway and subsequent proinflammatory state [28], a … However, other studies
did not provide any evidence of … to TCDD and PCBs, BPA led to augmented GSIS in vivo in a …

Exposure to PCB126 during the nursing period reversibly impacts early-life glucose tolerance

BB Rice, KW Sammons, SY Ngo Tenlep… - Frontiers in …, 2023 - frontiersin.org
evidence demonstrating the detrimental effects PCB exposure … Non-ortho substituted PCBs
or coplanar PCBs are more … (33) and the profiles of pro-inflammatory cytokines and hormones …