… mono-ortho PCBs have coplanar structures that make them more toxic since they bind with
higher affinity the AhR receptor. For this reason non-ortho and mono-ortho PCBs have been …

… the expression of pro-inflammatory cytokines as well as ROS … Evidence that the AhR
pathway is functional comes from the … the fish immune response to coplanar PCBs is age-dependent…

… proof-of-concept study [14]. A category of strong AhR agonists is the polychlorinated biphenyls
(PCBs), … Here, we used a typical inducer of the AhR pathway, a co-planar polychlorinated …

… For PCBs and PBDEs, there was no conclusive evidence that … Higher PCB exposure was
associated with increasing weight in … differentiation and pro-inflammatory adipokine expression. …

… human, experimental and mechanistic evidence on agents suspected of inducing cancer
in humans, using a well-established weight of evidence approach. The monographs provide …

… signaling pathway and subsequent proinflammatory state [28], a … However, other studies
did not provide any evidence of … to TCDD and PCBs, BPA led to augmented GSIS in vivo in a …

… Most in vivo and in vitro studies have been concentrated on various aspects related to
neurons (eg neuroprotection), however, there has not been focus on the prevention of early …

… evidence demonstrating the detrimental effects PCB exposure … Non-ortho substituted PCBs
or coplanar PCBs are more … (33) and the profiles of pro-inflammatory cytokines and hormones …

… There is credible evidence that environmental factors influence individual risk and/or severity
of … autism risk and/or severity using polychlorinated biphenyls (PCBs) as an example. …

… Recent evidence shows that they may be activated by human CYP1A1 for clastogenic … In
this study, pretreatment of HepG2 cells with PCB 126 potentiated the micronucleus formation by …