[HTML][HTML] Current trends and future prospects of molecular targeted therapy in head and neck squamous cell carcinoma

N Kitamura, S Sento, Y Yoshizawa, E Sasabe… - … journal of molecular …, 2020 - mdpi.com
… in predicting prognosis in head and neck cancer. In particular, the … The most promising gene
panel test for cancer is the … standard treatment are subject to a gene panel test for cancer, so …

Clinical development of molecular targeted therapy in head and neck squamous cell carcinoma

P Gougis, C Moreau Bachelard, M Kamal… - JNCI Cancer …, 2019 - academic.oup.com
… In head and neck oncology, cetuximab that targets epidermal growth factor … molecular
targeted therapy in HNSCC and to discuss how it could be accelerated by exploiting the molecular

[HTML][HTML] Clinical update on head and neck cancer: molecular biology and ongoing challenges

E Alsahafi, K Begg, I Amelio, N Raulf, P Lucarelli… - Cell death & …, 2019 - nature.com
… To obtain the best experience, we recommend you use a … and the only available targeted
therapy, and subsequent … and to develop more effective targeted therapies. However, as …

PI3K/AKT/mTOR signaling as a molecular target in head and neck cancer

FE Marquard, M Jücker - Biochemical pharmacology, 2020 - Elsevier
… ) with cisplatin and radiotherapy has reported promising 2-year progression free survival
and … Therefore, further investigations, particularly in targeted therapy, are needed. PI3K/AKT/…

[HTML][HTML] Therapeutic approaches for the treatment of head and neck squamous cell carcinoma–An update on clinical trials

B Goel, AK Tiwari, RK Pandey, AP Singh, S Kumar… - … Oncology, 2022 - Elsevier
… So far, the most promising treatment is a combination of … the efficacy of immunotherapy
and molecular targeted treatments. … Immunotherapy for head and neck cancer offers patients, …

Head and neck cancer: Current challenges and future perspectives

GR Bhat, RG Hyole, J Li - Advances in Cancer Research, 2021 - Elsevier
… will be key to develop more effective targeted therapies with less toxicity and high specificity.
… have a promising prognosis. However, the mainstays of treatment for advanced tumors are …

[HTML][HTML] Molecular landscape of head and neck cancer and implications for therapy

CS Farah - Annals of Translational Medicine, 2021 - ncbi.nlm.nih.gov
… The elevated expression of EGFR in OSCC makes it an attractive molecular target for
treatment. Cetuximab, is an approved targeted therapy for HNSCC, including advanced OSCC. …

[HTML][HTML] EGFR in head and neck squamous cell carcinoma: exploring possibilities of novel drug combinations

HS Rehmani, N Issaeva - Annals of translational medicine, 2020 - ncbi.nlm.nih.gov
cancer, it was natural to assume that head and neck cancer patients may benefit from
EGFR-targeted therapies… a hopeful finding. Currently there are no clinical trials using Osimertinib …

[HTML][HTML] The head and neck squamous cell carcinoma microenvironment as a potential target for cancer therapy

J Plzák, J Bouček, V Bandúrová, M Kolář, M Hradilová… - Cancers, 2019 - mdpi.com
… of the microenvironment of head and neck cancer with … L1 therapy with targeting other
receptors such as lectin-like inhibitory receptor NKG2A or EGFR seems to be promising for therapy

Review of emerging biomarkers in head and neck squamous cell carcinoma in the era of immunotherapy and targeted therapy

JCH Hsieh, HM Wang, MH Wu, KP Chang… - Head & …, 2019 - Wiley Online Library
… While these cancers are conventionally defined as members of the family of head and neck
cancers, they are generally thought of as different entities from HNSCC. The main reasons …