[PDF][PDF] Differential and Common Signatures of miRNA Expression and Methylation in Childhood Central Nervous System Malignancies: An Experimental and …

GI Lambrou, M Poulou, K Giannikou, M Themistocleous… - 2021 - academia.edu
… investigation of the promoter methylation of a set of tumor suppressor and apoptotic genes.
The gene repertoire examined included the promoters of CASP8, RASSF1, MGMT, MSH6, …

Differential and Common Signatures of miRNA Expression and Methylation in Childhood Central Nervous System Malignancies: An Experimental and Computational …

GI Lambrou, M Poulou, K Giannikou, M Themistocleous… - Cancers, 2021 - mdpi.com
… investigation of the promoter methylation of a set of tumor suppressor and apoptotic genes.
The gene repertoire examined included the promoters of CASP8, RASSF1, MGMT, MSH6, …

Tumors of the Nervous System: General Considerations

S Weis, M Sonnberger, A Dunzinger… - Imaging Brain Diseases …, 2019 - Springer
… includes histone modifications and DNA methylation. … common in such tumors as
medulloblastoma and ganglioglioma. … MGMT promoter methylation is the key mechanism of MGMT

The role of epigenetic modifications in human cancers and the use of natural compounds as epidrugs: Mechanistic pathways and pharmacodynamic actions

A Bouyahya, H Mechchate, L Oumeslakht, I Zeouk… - Biomolecules, 2022 - mdpi.com
… /Apo1/CD95, DAPK, Caspase-8) could be an important mechanism … of a DNA
methylation-silenced gene, E-cadherin, in MDA-MB… EGCG mediated epigenetic induction of …

Initiation of wound healing is regulated by the convergence of mechanical and epigenetic cues

T Bhatt, R Dey, A Hegde, AA Ketkar… - PLoS …, 2022 - journals.plos.org
… We observed that tension release by disrupting calcium-dependent E-cadherin junctions via
… to the acute increase in the caspase-8 promoter methylation as a potential mechanism of …

The initiation of the wound healing program is regulated by the convergence of mechanical and epigenetic cues

T Bhatt, R Dey, AM Hegde, AA Ketkar, AJ Pulianmackal… - bioRxiv, 2021 - biorxiv.org
… We observed that tension release by disrupting calcium-dependent E-cadherin junctions via
… to the acute increase in the caspase-8 promoter methylation as a potential mechanism of …

Association of caspase-8 genotypes with bladder cancer risk

M Chen, YT Tsai, WS Chang, LC Shih… - Anticancer …, 2019 - ar.iiarjournals.org
Background/Aim: Rs3824129 is a functional six-nucleotide insertion(I)/deletion(D)
polymorphism in the promoter region of caspase 8, an essential apoptosis gene. We aimed to …

Epigallocatechin-3-gallate therapeutic potential in cancer: mechanism of action and clinical implications

M Kciuk, M Alam, N Ali, S Rashid, P Głowacka… - Molecules, 2023 - mdpi.com
… -apoptotic factors such as caspase-8 inhibitor cellular FLICE-… CDH1 (E-cadherin), is a
molecule crucial for cell adhesion, … trimethylation enrichment at the TIMP-3 promoter, along with a …

[PDF][PDF] CASPASE IN NEUROLOGICAL DISEASE

E Wiyarta, RA Budiman, T Tango, SAS Ghozali… - 2022 - researchgate.net
… Survival of tumor cells in medulloblastoma is favored due to the possible the inactivation
of caspase-8 through the methylation of the 5’ UTR promoter region for the expression of …

MicroRNA-Expressions-und DNA-Methylierungsuntersuchungen im Primärtumor und Rezidiv des Glioblastoma multiforme

ML Schürgers - 2021 - publikationen.sulb.uni-saarland.de
… The present work investigated miRNA expressions and DNA methylation in primary and …
realtime PCR, the methylation status of p15, p16 and MGMT by methylation-specific PCR. For …