The role of epigenetic dysregulation in suicidal behaviors
LM Fiori, G Turecki - Behavioral Neurobiology of Suicide and Self Harm, 2020 - Springer
… The first study investigating BDNF in suicide examined methylation of the promoter/exon
IV regions in the brain Wernicke area of people who died by suicide and found …
IV regions in the brain Wernicke area of people who died by suicide and found …
DNA methylation and hydroxymethylation and behavior
… hypermethylation in the promoter regions of ribosomal RNAs … a gene-specific increase of
DNA methylation downregulates … account for the pathophysiology observed the suicidal brain. …
DNA methylation downregulates … account for the pathophysiology observed the suicidal brain. …
Characterization of Cerebellum-Specific Ribosomal DNA Epigenetic Modifications in Alzheimer's Disease: Should the Cerebellum Serve as a Control Tissue After All?
TC Faria, HL Maldonado, LC Santos, R DeLabio… - Molecular …, 2020 - Springer
… methylation is the mechanism involved in rRNA expression regulation in AD. Hence, we
sought to explore the rDNA methylation pattern of two different brain … ribosomal RNA genes are …
sought to explore the rDNA methylation pattern of two different brain … ribosomal RNA genes are …
Epigenetic studies in suicidal ideation and behavior
… disorder and SCZ Discovered hypermethylation in the promoter region of the TrkB gene, as
well … of histone 3 Lysine 27 in the brains of suicide victims compared to non-suicide controls. …
well … of histone 3 Lysine 27 in the brains of suicide victims compared to non-suicide controls. …
Epigenetics of suicidal behaviors
LM Fiori, G Turecki - Alternatives to Suicide, 2020 - Elsevier
… They identified three regions that were differentially methylated in both brain areas, mapping
to the genes psoriasis susceptibility 1 candidate 3 (PSORS1C3), TAP binding protein (…
to the genes psoriasis susceptibility 1 candidate 3 (PSORS1C3), TAP binding protein (…
The Structure, Expression, and Non-Canonical Functions of Human rDNA: The Role of Non-Coding Regions
AA Sadova, DY Panteleev, GV Pavlova - Molecular Biology, 2023 - Springer
… fact that ribosomal genes coding for ribosomal RNAs (rRNAs)… reduced rRNA production,
are characteristic to suicide … and increased rRNA synthesis are observed in the brains of folate-…
are characteristic to suicide … and increased rRNA synthesis are observed in the brains of folate-…
Early-life adversity, suicide risk and epigenetics of trauma
CA Alfonso, TG Schulze - Suicide by self-immolation: Biopsychosocial and …, 2021 - Springer
… Epigenetic mechanisms associated with suicide include DNA methylation, … in brains of
those who died by suicide, including MRI and functional imaging studies of persons with suicidal …
those who died by suicide, including MRI and functional imaging studies of persons with suicidal …
Neurexin 1: Risk Factor for Suicide Death
N William - 2020 - search.proquest.com
… , more commonly, methylation, which influences cell-specific gene expression. For example,
… adrenergic receptors in multiple brain regions in depressed suicides and controls, reporting …
… adrenergic receptors in multiple brain regions in depressed suicides and controls, reporting …
Epigenetic alterations associated with childhood trauma and adult mental health outcomes: A systematic review
… dataset from the Quebec Suicide Brain Bank. The ribosomal RNA (rRNA) gene and spindle
and … One study investigated genome-wide methylation profiles, in the Quebec Suicide Brain …
and … One study investigated genome-wide methylation profiles, in the Quebec Suicide Brain …
Epigenomic mediation after adverse childhood experiences: a systematic review and meta-analysis
I Neves, RJ Dinis-Oliveira… - Forensic sciences …, 2021 - academic.oup.com
… [57] studied methylation of the kappa opioid receptor (OPRK1) using brain tissue of suicide
victims with and without a history of child sexual and physical abuse and neglect compared …
victims with and without a history of child sexual and physical abuse and neglect compared …