… The first study investigating BDNF in suicide examined methylation of the promoter/exon
IV regions in the brain Wernicke area of people who died by suicide and found …

… hypermethylation in the promoter regions of ribosomal RNAs … a gene-specific increase of
DNA methylation downregulates … account for the pathophysiology observed the suicidal brain. …

… methylation is the mechanism involved in rRNA expression regulation in AD. Hence, we
sought to explore the rDNA methylation pattern of two different brain … ribosomal RNA genes are …

… disorder and SCZ Discovered hypermethylation in the promoter region of the TrkB gene, as
well … of histone 3 Lysine 27 in the brains of suicide victims compared to non-suicide controls. …

… They identified three regions that were differentially methylated in both brain areas, mapping
to the genes psoriasis susceptibility 1 candidate 3 (PSORS1C3), TAP binding protein (…

… fact that ribosomal genes coding for ribosomal RNAs (rRNAs)… reduced rRNA production,
are characteristic to suicide … and increased rRNA synthesis are observed in the brains of folate-…

… Epigenetic mechanisms associated with suicide include DNA methylation, … in brains of
those who died by suicide, including MRI and functional imaging studies of persons with suicidal …

… , more commonly, methylation, which influences cell-specific gene expression. For example,
… adrenergic receptors in multiple brain regions in depressed suicides and controls, reporting …

… dataset from the Quebec Suicide Brain Bank. The ribosomal RNA (rRNA) gene and spindle
and … One study investigated genome-wide methylation profiles, in the Quebec Suicide Brain …

… [57] studied methylation of the kappa opioid receptor (OPRK1) using brain tissue of suicide
victims with and without a history of child sexual and physical abuse and neglect compared …