Propolis relieves the cardiotoxicity of chlorpyrifos in diabetic rats via alleviations of paraoxonase-1 and xanthine oxidase genes expression

KA Ibrahim, SA Khwanes, MA El-Desouky… - Pesticide biochemistry …, 2019 - Elsevier
streptozotocin) and chlorpyrifos (2.5 mg/kg), respectively. The 5th was diabetes/chlorpyrifos
combination, while 6th, 7th, and 8th were intubated with propolis … and STZ individually didn't …

[HTML][HTML] Phenolics from Physalis peruviana fruits ameliorate streptozotocin-induced diabetes and diabetic nephropathy in rats via induction of autophagy and …

SM Ezzat, HMI Abdallah, NN Yassen… - Biomedicine & …, 2021 - Elsevier
STZ is a broad-spectrum antibiotic that is toxic to … pancreatic β cells bringing about
degranulation and loss of the ability to secrete insulin [67], [68]. Thus, in the present investigation, …

[HTML][HTML] An overview of the evidence and mechanism of drug–herb interactions between propolis and pharmaceutical drugs

S Hossain, M Yousaf, Y Liu, D Chang… - Frontiers in …, 2022 - frontiersin.org
propolis by scavenging ROS and increased production of anti-oxidant enzymes protected
multi-organs in the body against the toxicitySTZ-induced mice compared with using propolis

[HTML][HTML] Modulatory effect of caffeic acid in alleviating diabetes and associated complications

R Ganguly, SV Singh, K Jaiswal, R Kumar… - World Journal of …, 2023 - ncbi.nlm.nih.gov
… by the dysfunction of pancreatic β-cells with complete loss of … STZ-induced diabetic mice
Topical administration of propolis … Since propolis found in beehive is a major source of CAPE, …

Protective effects of Artemisia judaica extract compared to metformin against hepatorenal injury in high-fat diet/streptozotocine-induced diabetic rats

G Albasher, M Alwahaibi, MM Abdel-Daim… - … science and pollution …, 2020 - Springer
… extract (AjE) against hepatorenal damage in a high-fat diet/streptozotocin (HFD/STZ) rat model
… stimulates insulin secretion from β cells, activates AMPK and suppresses inflammation. J …

The protective effect of Satureja bachtiarica hydroalcoholic extract on streptozotocin‐induced diabetes through modulating glucose transporter 2 and 4 expression …

R Joudaki, M Setorki - Pharmaceutical biology, 2019 - Taylor & Francis
STZ is taken up by the pancreatic β-cellsthe pancreatic β-cells and degrades to carbonium
radicals. Carbonium radicals are highly reactive and induce direct toxic effects on pancreatic

[HTML][HTML] Evaluation of pancreatic regeneration activity of Tephrosia purpurea leaves in rats with streptozotocin-induced diabetes

SK Arora, PR Verma, PR Itankar, SK Prasad… - Journal of Traditional …, 2021 - Elsevier
… was undertaken to evaluate pancreatic β-cells regeneration, … are the major causes of glucose
toxicity. Decreased levels of insulin … were decreased in pancreas and blood in STZ-induced …

[PDF][PDF] Brassinin Exhibits Anti-Diabetic Activity against Streptozotocin-induced Diabetes Mellitus in Experimental Rats

BX Xu, AA Alarfaj, AH Hirad, N Natarajan, P Iyappan… - Indian J. Pharm …, 2023 - ijper.org
… substance called STZ, which damages the β-cells present in … insulin from the residual
pancreatic β-cells. By enhancing the … effects of Malaysian propolis and metformin in streptozotocin-…

[PDF][PDF] Propolis in Metabolic Syndrome and Its Associated Chronic Diseases: A Narrative Review. Antioxidants 2021, 10, 348

F Zulhendri, M Ravalia, K Kripal, K Chandrasekaran… - 2021 - scienceopen.com
… The term “propolis” in this review study includes propolis from all … Propolis protects
pancreatic β-cells against the toxicity of streptozotocin (STZ). Phytomedicine 1996, 3, 203–209. […

Recent advances in the chemical composition and biological activities of propolis

O Belmehdi, N El Menyiy, A Bouyahya… - Food Reviews …, 2023 - Taylor & Francis
… In streptozotocin (STZ)-induced diabetic rats, Brazilian propolis at … propolis supplementation
(0.3 g/Kg/day) against the toxic effect of STZ on pancreatic β-cells and showed that propolis