[HTML][HTML] An investigation into the potential action of polyphenols against human Islet Amyloid Polypeptide aggregation in type 2 diabetes

A Mahboob, DKL Senevirathne, P Paul, F Nabi… - International Journal of …, 2023 - Elsevier
… and dysfunction in pancreatic β-cells. In healthy individuals, β-cells produce insulin which is
a … In individuals with T2D, the β-cells are either dysfunctional or their mass is reduced, thus …

[PDF][PDF] Investigation of the protective and therapeutic effects of β-aminoisobutyric acid (BAIBA) and Thymoquinone in the diabetic nephropathy.

İ Aktaş, FM Gür - Boletín Latinoamericano y del Caribe de Plantas …, 2021 - researchgate.net
… The mechanism of the action of STZ on pancreatic β-cells has … development of complications
from STZ (Sadek et al., 2017). … Carboxylic radicals, which are highly reactive, produce toxic

[HTML][HTML] Possible Synergistic Antidiabetic Effects of Quantified Artemisia judaica Extract and Glyburide in Streptozotocin-Induced Diabetic Rats via Restoration of …

AS Saeedan, GA Soliman, RF Abdel-Rahman… - Biology, 2021 - mdpi.com
… a synergistic activity against oxidative stress and LPO in pancreatic tissues of STZ-control
animals. … and MDA in the pancreatic homogenates may protect β-cells against ROS and LPO. …

[HTML][HTML] Fecal metabolomics reveals the positive effect of ethanol extract of propolis on T2DM mice

C Wang, H Zhao, K Xu, Y Du, J Liu, J Wang… - Food Science and …, 2023 - Elsevier
… the inability of β cells to compensate for IR (pancreatic β cell … Streptozotocin (STZ) and edible
PEG-20000 were purchased … This study was carried out in HFD joint induced by STZ; it is a …

Amelioration of streptozotocin-induced neurotoxicity in rats by a standardized extract of Cydonia oblonga seeds.

R Anwar, DA Gulzar… - … Journal of Medical …, 2022 - search.ebscohost.com
… viral attack, toxic chemical agents or by autoimmune antibodies.Streptozotocin (STZ) is a
diabetogenic chemical that stimulates pancreatic β cells injury and induces hyperglycemia. The …

[HTML][HTML] Anti-inflammatory phytochemicals for the treatment of diabetes and its complications: Lessons learned and future promise

M Kong, K Xie, M Lv, J Li, J Yao, K Yan, X Wu… - Biomedicine & …, 2021 - Elsevier
… nonetheless also include poisonous and toxic chemicals. … Contrary to α cells, pancreatic
β cells possess a high … In diabetic animal models induced by streptozotocin (STZ), berberine …

[HTML][HTML] Galangin attenuates liver injury, oxidative stress and inflammation, and upregulates Nrf2/HO-1 signaling in streptozotocin-induced diabetic rats

W Al-Amarat, MH Abukhalil, OY Althunibat… - Processes, 2021 - mdpi.com
… Diabetes was induced by streptozotocin (STZ), and the rats … effects against cyclophosphamide
(CP) toxicity by preventing … to further destruction of the β-cells and worsening the glycemic …

Antidiabetic and antioxidant effects of tannic acid and melatonin on streptozotocin induced diabetes in rats.

EM Esmaiel, AM Abo-Youssef… - Pakistan Journal of …, 2019 - search.ebscohost.com
… acid and melatonin in streptozotocin (STZ) induced diabetes in … treatment induces pancreatic
β-cells regeneration which … lyophilized aqueous extract of propolis from Erzurum Turkey. …

[HTML][HTML] … evaluation of the preclinical efficacy of Solanum torvum Swartz leaves for treating oxidative impairment in rats administered a β-cell-toxicant (STZ)

S Sani, B Lawal, JN Ejeje, TB Aliu, AS Onikanni… - Biomedicine & …, 2022 - Elsevier
… impairment in streptozotocin (STZ)-intoxicated rats. Rats with … of free radicals cause
destruction of pancreatic β-cells [6], … are characterized by ineffectiveness and toxic side effects on …

Antidiabetic Effects of Coffee Silverskin Extract in Streptozotocin-Induced Diabetic Wistar Rats

CEH Barka, B Bensenane, H Merzouk… - Waste and Biomass …, 2024 - Springer
… Supplementation with non-toxic free radical scavengers and antioxidants may facilitate
the regeneration of β-cells and protect pancreatic islets against the cytotoxic effects of STZ [7]. …