Antioxidative and Antidiabetic Effect of Goldenberries juice and pomace on Experimental Rats Induced with streptozotocin In Vitro.

AG Darwish, HI Mahmoud, IH Refaat - Journal of Food and Dairy …, 2020 - journals.ekb.eg
… of streptozotocin (STZ) 65 mg/kg bw Three days after STZ … , which prevent the pancreatic
β-cells injury and motivate the … epicatechin protects the construction of pancreatic β-cells

Algerian Capparis spinosa n-buoh extract alleviates diabetic neuropathy induced with streptozotocin in rats

I Sakrani, S Ameddah, M Benrebaia… - Egyptian Journal of …, 2022 - journals.ekb.eg
toxic effects on pancreatic islet cells by increasing the ROS formation [118]. Several investigations
have shown that STZ enters the pancreatic β-cells … producing islet β-cells and inducing …

The Antidiabetic Effect of Nigella sativa L. with Respect to Its Phytochemicals and the Mechanism of Action

IZ Ahmad - Antidiabetic Plants for Drug Discovery, 2022 - taylorfrancis.com
… were used to observe the pancreatic β-cells. It was seen that STZ has induced a considerable
… The antidiabetic activity of Nigella sativa and propolis on streptozotocin-induced diabetes …

Trans-3, 5-dicaffeoylquinic acid from Geigeria alata Benth. & Hook. f. ex Oliv. & Hiern with beneficial effects on experimental diabetes in animal model of essential …

R Simeonova, V Vitcheva, D Zheleva-Dimitrova… - Food and chemical …, 2019 - Elsevier
… function and improvement of antioxidant status in streptozotocin (STZ)-induced diabetic rats.
… the diabetogenic effect of STZ (Szkudelski, 2001). The pancreatic β-cells possess both low …

Flavonoids and type 2 diabetes: Evidence of efficacy in clinical and animal studies and delivery strategies to enhance their therapeutic efficacy

T Hussain, B Tan, G Murtaza, G Liu, N Rahu… - Pharmacological …, 2020 - Elsevier
… reductase by carbohydrate metabolic pathway in pancreatic β-cells, hepatocytes, adipocytes
and … tools must be employed to develop drug exerts less toxic effects [18]. This review paper …

Effect of CAPE-pNO2 against type 2 diabetes mellitus via the AMPK/GLUT4/GSK3β/PPARα pathway in HFD/STZ-induced diabetic mice

S Li, Q Huang, L Zhang, X Qiao, Y Zhang… - European journal of …, 2019 - Elsevier
… diet (HFD) before injection of 40 mg/kg streptozotocin (STZ) for five days, and the normal diet
mice … Caffeic acid phenethyl ester (CAPE), a main active ingredient of propolis, has multiple …

[HTML][HTML] Pharmacological effects of gallic acid in health and diseases: A mechanistic review

N Kahkeshani, F Farzaei, M Fotouhi… - Iranian journal of …, 2019 - ncbi.nlm.nih.gov
… , reduces the size of adipocytes, and protects pancreatic β-cells by inducing the expression
of … The compound restores the streptozotocin (STZ)-induced cerebellar oxidative stress and …

[HTML][HTML] Mechanisms of action of natural products on type 2 diabetes

T Wang, YY Wang, MY Shi, L Liu - World Journal of Diabetes, 2023 - ncbi.nlm.nih.gov
… exhibiting resistance to the toxicity of cobalt chloride[42,43]. … of pancreatic β cells, and
exerts its antiapoptotic effect on STZ-… These results indicated that propolis increased the serum …

[HTML][HTML] Esculeoside A alleviates reproductive toxicity in streptozotocin-diabetic rats's model by activating Nrf2 signaling

JZ AlTamimi, NA AlFaris, GM Alshammari… - Saudi Journal of …, 2023 - Elsevier
… of Nrf2 triggers the protective potential of ESA against reproductive toxicity in STZ-DM rats. …
The streptozotocin (STZ) diabetic animal model induced by single or multiple doses of STZ

Arbutin alleviates diabetic symptoms by attenuating oxidative stress in a mouse model of type 1 diabetes

H Li, W Cao, LF Wei, JQ Xia, Y Gu, LM Gu… - International Journal of …, 2021 - Springer
… This study analyzed the effects of arbutin on streptozotocin (STZ)-induced diabetes mellitus
… The toxic conditions in hyperglycemia disrupt pancreatic β-cells, leading to a reduction of …