Effects of nebivolol versus other antihypertensive drugs on the endothelial dysfunction in patients with essential hypertension

B Li, Q Zhang, H Zhang, C Wang, R Xiu - Bioscience Reports, 2020 - portlandpress.com
… that nebivolol did not have a better endothelium-protective effectNebivolol is not a unique
endothelial function-protective agent … Reversal of endothelial dysfunction is a key point in the …

Treatment with β-blocker nebivolol ameliorates oxidative stress and endothelial dysfunction in tenofovir-induced nephrotoxicity in rats

MM Nascimento, DRD Bernardo… - Frontiers in …, 2022 - frontiersin.org
… renal function, induced hypertension, endothelial dysfunction … of nebivolol lowered MAP and
reversed endothelial dysfunction… isoforms by nebivolol contributes to its protective effects on …

Nebivolol Alleviates Vascular Endothelial Insulin Resistance by Inhibiting Endoplasmic Reticulum Stress

X Li, Q Li, L Wu, Y Wang - International Heart Journal, 2023 - jstage.jst.go.jp
… Further, endothelial dysfunction can cause endothelial IR. … eased dyslipidemia in GK rats
without affecting blood pressure, … The protective effect of silk fibroin on high glucose induced …

Does nebivolol have renoprotective action in patients with chronic kidney disease conditions? An integrative review

JFA Encinas, CHF Peiro, MM Perez… - European Journal of …, 2021 - Elsevier
… on whether it exerts a protective effect in the kidneys or not. In … of NEB partially reversed
endothelial dysfunction in the renal … to be altered in hypertensive and/or diabetic patients, and …

Effect of nebivolol on microalbuminuria in hypertensive patients with or without type 2 diabetes mellitus

PL Merugu, TC Bingi - Journal of Pharmacology and …, 2020 - journals.sagepub.com
… renal‑protective effects of this class of drugs.[8,9] However, these agents are … hypertensive
patients with endothelial dysfunction showed that nebivolol reverses endothelial dysfunction

Mechanisms and clinical implications of endothelial dysfunction in arterial hypertension

P Ambrosino, T Bachetti, SE D'Anna… - Journal of …, 2022 - mdpi.com
… The protective effect of CCBs on cardiovascular risk in … as an outcome measure, nebivolol
has shown a positive impact on endothelialReversal by calcium channel blockade but not by …

Inhibition of eNOS Partially Blunts the Beneficial Effects of Nebivolol on Angiotensin II-Induced Signaling in H9c2 Cardiomyoblasts

R Gul, N Alsalman, AA Alfadda - Current Issues in Molecular Biology, 2022 - mdpi.com
Endothelial dysfunction provoked by a NO and Ang II … -mediated protective effects, we tested
the effects of the L-… features make nebivolol a better drug of choice to control hypertension, …

Enhanced eNOS/nitric oxide production by nebivolol interferes with TGF-β1/Smad3 signaling and collagen I deposition in the kidney after prolonged tacrolimus …

AA Azouz, MA Tohamy, FEM Ali, HM Mahmoud - Life Sciences, 2024 - Elsevier
… partly attributed to endothelial dysfunction alongside decreased … The protective effects of
nebivolol were further confirmed by … with nebivolol increased plasma NO levels in hypertensive

Comparative beneficial effects of nebivolol and nebivolol/valsartan combination against mitochondrial dysfunction in angiotensin II-induced pathology in H9c2 …

R Gul, N Alsalman, A Bazighifan… - Journal of Pharmacy …, 2021 - academic.oup.com
… The protective effects of valsartan in hypertensive patients are … the observed protective
effects of nebivolol or nebivolol/… In addition, nebivolol reverses endothelial dysfunction by …

Nebivolol in oral subacute treatment prevents cardiac post-ischemic dysfunction in rats, but hyperthyroidism reduces this protection: mechanisms involved

MI Ragone, M Bayley, S López, RG Díaz… - Naunyn-Schmiedeberg's …, 2024 - Springer
… prevented dysfunction in HpT hearts but partially in EuT hearts. Nebivolol effects were reversed
… the protective effect of nebivolol in HpT hearts, but reduced the protection in EuT hearts. …