Coronary artery disease and endothelial dysfunction: novel diagnostic and therapeutic approaches

E Oikonomou, G Siasos, V Tsigkou… - Current Medicinal …, 2020 - ingentaconnect.com
… factors such as hyperlipidemia, diabetes, smoking, and hypertension improves endothelial
Again, a randomized study indicated that therapy with 5 mg nebivolol for 4 weeks significantly …

A molecular network-based pharmacological study on the protective effect of Panax notoginseng rhizomes against renal ischemia–reperfusion injury

DD Li, N Li, C Cai, CM Wei, GH Liu… - Frontiers in …, 2023 - frontiersin.org
… to explore the protective effect of Panax notoginseng rhizomes (PNR) on renal ischemia and
reperfusion injury (… The reverse transcription reaction system was prepared according to the …

Nebivolol/valsartan combination for the treatment of hypertension: a review

SJ Wang, GE Sander - Future Cardiology, 2020 - Future Medicine
… by which N might reduce and reverse cardiovascular dysfunction is of great importance. …
II-induced (AngII) hypertension with severe endothelial dysfunction and a significant impairment …

Irisin lowers blood pressure in Zucker diabetic rats by regulating the functions of renal angiotensin II type 1 receptor via the inhibition of the NF-κB signaling pathway

Y Huang, Q Chen, Q Jiang, Z Zhao, J Fang, L Chen - Peptides, 2022 - Elsevier
… These effects were profoundly reversed by irisin … ) rats, by improving the endothelial function
of the mesenteric artery … In our study, the data showed that irisin exerted a protective effect

The Impact of Pharmacotherapy for Heart Failure on Oxidative Stress—Role of New Drugs, Flozins

P Bodnar, M Mazurkiewicz, T Chwalba, E Romuk… - Biomedicines, 2023 - mdpi.com
dysfunction and remodeling, and endothelial dysfunction. One … -related mortality, irrespective
of the effect on blood pressure. … a protective effect against H 2 O 2 -induced cell damage by …

Endothelial dysfunction and cardiovascular diseases through oxidative stress pathways

R Rodríguez-Guzmán, EMC Miranda… - … in Vascular Dysfunction …, 2021 - Elsevier
nebivolol that reduce blood pressure can stimulate NO production and thus improve
endothelial function … In contrast, the protective ability of HDL arises from reverse transport of …

Hypertension in metabolic syndrome: novel insights

A Katsimardou, K Imprialos… - … Hypertension …, 2020 - ingentaconnect.com
… mellitus, the administration of nebivolol improved almost all the … a protective effect against
the negative metabolic effects of … Endothelial dysfunction in metabolic syndrome: Prevalence, …

Diverse pharmacological properties, trial results, comorbidity prescribing and neural pathophysiology suggest European hypertension guideline downgrading of beta …

M Esler, SE Kjeldsen, A Pathak, G Grassi, R Kreutz… - … Pressure, 2022 - Taylor & Francis
… fully exploiting the documented protective effect of BP lowering “per … SNS is modulating
endothelial function. In free-moving … , sustained release metoprolol and nebivolol to be the beta-…

[HTML][HTML] Ivabradine and blood pressure reduction: underlying pleiotropic mechanisms and clinical implications

F Simko, T Baka - Frontiers in Cardiovascular Medicine, 2021 - frontiersin.org
… stress with high tensile stress triggering endothelial dysfunction (3). … These potentially
protective effects of ivabradine could result … A well-tailored dosing of ivabradine might reverse non-…

[HTML][HTML] Direct comparison of inorganic nitrite and nitrate on vascular dysfunction and oxidative damage in experimental arterial hypertension

P Stamm, M Oelze, S Steven, S Kroeller-Schoen… - Nitric Oxide, 2021 - Elsevier
protective effects of inorganic nitrite and nitrate in an animal model of arterial hypertension.
… In the present study, we confirmed higher blood pressure, deterioration of endothelial function