[HTML][HTML] Short-term pharmacological activation of Nrf2 ameliorates vascular dysfunction in aged rats and in pathological human vasculature. A potential target for …

J Angulo, M El Assar, A Sevilleja-Ortiz… - Redox Biology, 2019 - Elsevier
… Some evidences point to endothelial protective effects by … SFN) endothelial impairment was
completely reversed by SFN, … endothelial function in situations associated with endothelial

Protective Effects of Telmisartan and Trimetazidine in Isoproterenol-Induced Myocardial Hypertrophy in Rats: Role of Autophagy

IM Radwan, HMF Mohammad, S Makary… - Suez Canal …, 2022 - journals.ekb.eg
… treatment of hypertension, congestive HF, and diabetic nephropathy(4). … endothelial dysfunction
via increasing nitric oxide and … Cardioprotective effects of curcumin and nebivolol against …

Mirabegron, a selective β3-adrenoceptor agonist causes an improvement in erectile dysfunction in diabetic rats

D Yilmaz-Oral, E Kaya-Sezginer… - … & Diabetes, 2021 - thieme-connect.com
… nerve, penile endothelial dysfunction, and veno-… that nebivolol was beneficial in the treatment
of diabetic neuropathy [15]. A study by Oikawa et al. [16] demonstrated protective effects of …

Renin-angiotensin system in pathogenesis of atherosclerosis and treatment of CVD

AV Poznyak, D Bharadwaj, G Prasad… - International Journal of …, 2021 - mdpi.com
… Oxidative stress is the main trigger of endothelial dysfunction, and, … effects, which are not
linked to blood pressure, as we … Long-term therapy with valsartan reversed atherosclerosis in …

Hypertension drug therapy

R Hui - Coronary Artery Disease: Therapeutics and Drug …, 2020 - Springer
… Flow-mediated dilation to measure endothelial function in … risk in patients with hypertension
can’t be completely reversed by BP … some protective effects on vascular or organ damage in …

[HTML][HTML] Ficus plants in the co-management of hypertension and erectile dysfunction

OF Ajeigbe, G Oboh, AO Ademosun - Phytomedicine Plus, 2021 - Elsevier
… penile arteries in hypertensive patients. This is accompanied by endothelial dysfunction
and … They improve endothelial function by reversing ED in animals by mitigating the NO/cGMP …

Sacubitril/valsartan reverses cardiac structure and function in experimental model of hypertension-induced hypertrophic cardiomyopathy

J Jeremic, N Govoruskina, J Bradic… - Molecular and Cellular …, 2023 - Springer
… Neprilysin inhibition might exert significant protective effects in hypertensive conditions.
Considering these facts, a dual-acting drug containing sacubitril and valsartan in a 1:1 molar …

Sacubitril/valsartan inhibits obesity-associated diastolic dysfunction through suppression of ventricular-vascular stiffness

AR Aroor, S Mummidi, JC Lopez-Alvarenga… - Cardiovascular …, 2021 - Springer
… Systolic blood pressure (SBP) and diastolic blood pressure … for nitric oxide-dependent
endothelial function. We observed … protective effects on DD through a previously unrecognized …

Nicorandil prevents the nephrotoxic effect of cyclosporine-A in albino rats through modulation of HIF-1α/VEGF/eNOS signaling

IA Harb, H Ashour, D Sabry… - Canadian Journal of …, 2021 - cdnsciencepub.com
… its renal effect on endothelial dysfunction targeting the hypoxia… Our hypothesis was to elucidate
the possible protective effect … and partially blocks the nicorandil effect on blood pressure. …

Mitochondrial effects of common cardiovascular medications: The good, the bad and the mixed

AM Bețiu, L Noveanu, IM Hâncu, A Lascu… - International Journal of …, 2022 - mdpi.com
… In streptozotocin-treated diabetic rats, nebivolol exhibits … did not elicit any protective effect
on mitochondrial function as … in an in vitro model of endothelial dysfunction in uremia [81]. In a …