… ketogenic activity and down-regulated ketolytic activity in … was more likely to work as a
ketogenic organ rather than a ketolytic organ. … Proteomics Analysis Reveals Diabetic Kidney as a …

… This possibility is particularly relevant to organ protection, since the effect of SGLT2 … favorable
effects in the diabetic kidney by promoting ketogenic nutrient deprivation signaling through …

… kidneys, nerves, cardiovascular, limbs, and other organs.1, 2 … By studying the renal cortical
proteome in db/db diabetic mice… , causing severe hypoglycemia, ketosis, and lactic acidosis. …

… This was supported by a decrease in MFN2 observed in our proteomic analysis (discussed in
… As introduced above, our proteomics analysis shows dysregulation of solute carriers, some …

… Though acylcarnitines are formed intracellularly in all organs and tissues except brain, there
is … Thus, comparative serum metabolomics analysis reveals complex defects in pathways of …

… , suggesting that the kidney may be a ketogenic organ. … diet induces extensive transcriptional
and proteomic responses … in mildly obese type 2 diabetic patients, although ketosis was …

… A ketogenic diet or mildly increased ketone body levels are … We carried out transcriptomics
and proteomics analysis to ex… for important organs such as the brain, heart and kidneys [7…

… the kidney cortex of the type 2 diabetic T2D db/db mice and that this process is regulated by
Sirtuin … Proteomic analysis of db/db and db/+ kidney cortex found that targets with significant …

… analysis revealed that canagliflozin induced alterations in amino acid metabolism profiles in
the renal tissue of diabetic … of a particular organ, and reveals alterations resulting from both …

… the main ketogenic organ, HMGCS2 is induced in the kidney … both potentially pathogenic
in diabetic nephropathy (5) and … of kidney HMGCS2 in fasting ketosis, we generated a kidney-…