[HTML][HTML] Psoriasis as an immune-mediated and inflammatory systemic disease: from pathophysiology to novel therapeutic approaches

A Campanati, A Marani, E Martina, F Diotallevi, G Radi… - Biomedicines, 2021 - mdpi.com
… in psoriasis considered as a systemic inflammatory disease? … association between multiple
sclerosis and psoriasis, an … The pathogenetic mechanism is unclear; however, a recent …

[HTML][HTML] Psoriasis and systemic inflammatory disorders

T Tashiro, Y Sawada - International journal of molecular sciences, 2022 - mdpi.com
… concerns which kinds of therapeutic options are better to regulate the development of systemic
inflammatory disorders. In the underlying mechanism of psoriasis, TNF-α or IL-23 are the …

Management of psoriasis as a systemic disease: what is the evidence?

NJ Korman - British Journal of Dermatology, 2020 - academic.oup.com
… symptoms but also reduce systemic inflammation, hence … the pathophysiological relationship
between psoriasis and its … effects of systemic inflammation in moderate‐to‐severe plaque …

[HTML][HTML] Immunology of psoriatic disease

E Reali, NC Brembilla - Frontiers in immunology, 2019 - frontiersin.org
… the “psoriasis march” represents the possible missing link: psoriasis is a systemic inflammatory
condition … Constantly more gaps are getting filled, and multiple novel mechanistic insights …

[HTML][HTML] The risk of systemic diseases in those with psoriasis and psoriatic arthritis: from mechanisms to clinic

YR Woo, CJ Park, H Kang, JE Kim - International Journal of Molecular …, 2020 - mdpi.com
… versa, the possible underlying mechanism of action between … to reduce the systemic
inflammation of psoriasis, we can … the development of various autoimmune disorders. However, to …

Chronic systemic inflammatory skin disease as a risk factor for cardiovascular disease

DA Bulger, S Minhas, AA Asbeutah, S Kayali… - Current Problems In …, 2021 - Elsevier
… in systemic inflammatory disease. Here we explore the current literature on psoriasis, … is
also more than likely some overlapping mechanism intracellularly that is shared amongst these …

[HTML][HTML] Role of skin and gut microbiota in the pathogenesis of psoriasis, an inflammatory skin disease

DK Hsu, MA Fung, HL Chen - Medicine in Microecology, 2020 - Elsevier
… microbiome play key roles in the pathogenesis of psoriasis. The aim of this review is to
identify a link between the microbial ecology of the gut and skin, and their relevance to psoriasis. …

[HTML][HTML] Adaptive and innate immunity in psoriasis and other inflammatory disorders

MP Schön - Frontiers in immunology, 2019 - frontiersin.org
autoimmune responses, together with our current view of psoriasis as a systemic inflammatory
disorder… would constitute a mechanism that regulates the fine-tuning between innate and …

The association of psoriasis and hypertension: focusing on anti‐inflammatory therapies and immunological mechanisms

MY Hu, Q Yang, J Zheng - Clinical and Experimental …, 2020 - academic.oup.com
… This review summarizes the mechanisms underlying the impact of systemic inflammation
on skin and arteries, and assesses the epidemiological and clinical links between psoriasis

Epigenetic factors involved in the pathophysiology of inflammatory skin diseases

L Möbus, S Weidinger, H Emmert - Journal of Allergy and Clinical …, 2020 - Elsevier
… (AD) and psoriasis (PSO) but … possible mechanism that could be influencing inflammation
is epigenetic regulation, but genome-wide epigenetic studies on inflammatory skin diseases