[HTML][HTML] Pulsed electromagnetic field stimulation of bone healing and joint preservation: cellular mechanisms of skeletal response
R Cadossi, L Massari, J Racine-Avila… - … Global Research & …, 2020 - journals.lww.com
The US FDA has approved pulsed electromagnetic fields (PEMFs) as a safe and effective
treatment for nonunions of bone. Despite its clinical use, the mechanisms of action of
electromagnetic stimulation of the skeleton have been elusive. Recently, cell membrane
receptors have been identified as the site of action of PEMF and provide a mechanistic
rationale for clinical use. This review highlights key processes in cell responses to PEMF as
follows:(1) signal transduction through A 2A and A 3 adenosine cell membrane receptors …
treatment for nonunions of bone. Despite its clinical use, the mechanisms of action of
electromagnetic stimulation of the skeleton have been elusive. Recently, cell membrane
receptors have been identified as the site of action of PEMF and provide a mechanistic
rationale for clinical use. This review highlights key processes in cell responses to PEMF as
follows:(1) signal transduction through A 2A and A 3 adenosine cell membrane receptors …
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