[HTML][HTML] From purines to purinergic signalling: molecular functions and human diseases

Z Huang, N Xie, P Illes, F Di Virgilio, H Ulrich… - Signal Transduction …, 2021 - nature.com
Purinergic signalling is cross-linked with other transmitter networks to … of purinergic signalling
contributes to various diseases including neurodegeneration, rheumatic immune diseases, …

[HTML][HTML] Eosinophils and purinergic signaling in health and disease

D Ferrari, M Vuerich, F Casciano, MS Longhi… - Frontiers in …, 2020 - frontiersin.org
… for purinergic receptors. Purinergic signaling represents an ubiquitous signal transduction
… Eosinophils express a wide range of purinergic receptors and purinergic receptor activation …

Introduction to purinergic signaling

G Burnstock - Purinergic Signaling: Methods and Protocols, 2020 - Springer
… Drury and Szent-Györgyi [6] showed extracellular actions of purines on heart and blood
vessels, papers by Feldberg showed extracellular actions of ATP on autonomic ganglia [7] and a …

[HTML][HTML] P2Y purinergic receptors, endothelial dysfunction, and cardiovascular diseases

D Strassheim, A Verin, R Batori, H Nijmeh… - International journal of …, 2020 - mdpi.com
… vasodilation in aged blood vessels was due to … purinergic signaling mechanisms in many
diseases. In contrast, fewer studies have been focused on purinergic signaling in vascular bed-…

Purinergic signalling in the kidney: In physiology and disease

MLT Monaghan, MA Bailey, RJ Unwin - Biochemical Pharmacology, 2021 - Elsevier
… renal purinergic signalling is … purinergic system to treat human disease. The research
discussed here demonstrates that abnormal purinergic signalling can contribute to kidney disease

[HTML][HTML] Role of purinergic signalling in endothelial dysfunction and thrombo-inflammation in ischaemic stroke and cerebral small vessel disease

NT Lee, LK Ong, P Gyawali, CMNCM Nassir… - Biomolecules, 2021 - mdpi.com
… Most organs such as the brain as well as the blood vessels of the circulatory system show
a continuous endothelial monolayer with a well-expressed continuous basement membrane …

Purinergic signaling in nervous system health and disease: Focus on pannexin 1

JC Sanchez-Arias, E van der Slagt… - Pharmacology & …, 2021 - Elsevier
… , behaviour, and neurological disease. We highlight examples of similarities and differences
between PANX1 and the spectrum of purinergic signaling players, and examine emerging …

[HTML][HTML] P2 purinergic signaling in the distal lung in health and disease

E Wirsching, M Fauler, G Fois, M Frick - International journal of molecular …, 2020 - mdpi.com
… cells express purinergic P2 receptors and that purinergic signaling plays important roles in
maintaining alveolar homeostasis. Therefore, it is not surprising that purinergic signaling also …

Alteration of purinergic signaling in diabetes: focus on vascular function

R Zhou, X Dang, RS Sprague, SJ Mustafa… - Journal of molecular and …, 2020 - Elsevier
… nucleot(s)ide-mediated purinergic signaling as an important disease mechanism for the
diabetes-associated vascular complications. Better … Purinergic transmission in blood vessels

Interplay between purinergic signalling and extracellular vesicles in health and disease

V Carotti, JP Rigalli, J van Asbeck-van der Wijst… - Biochemical …, 2022 - Elsevier
purinergic signalling at the target cells and tissues. Here, we review the studies addressing
the regulation of purinergic signalling … cargo by purinergic signalling. Here, a major role of the …