Emerging evidence of translational control by AU-rich element-binding proteins

H Otsuka, A Fukao, Y Funakami, KE Duncan… - Frontiers in …, 2019 - frontiersin.org
… RBPs bind specific motifs in their target mRNAs and regulate mRNA fate at many steps.
The AU-rich element (ARE) is one of the major cis-regulatory elements in the 3′ untranslated …

mRNA post-transcriptional regulation by AU-rich element-binding proteins in liver inflammation and cancer

D Dolicka, C Sobolewski, M Correia de Sousa… - International journal of …, 2020 - mdpi.com
… than 8% of all mRNAs and are thereby able to control the stability and/or … regulating mRNA
translation that are mediated by a class of RBPs called AU-rich element-binding proteins (…

[HTML][HTML] AU-rich element-binding proteins in colorectal cancer

N Legrand, DA Dixon, C Sobolewski - World Journal of …, 2019 - ncbi.nlm.nih.gov
… -acting factors controlling mRNA fate are critical for the post-transcriptional regulation of …
binding proteins” (AUBPs) control mRNA stability or translation through their binding to AU-rich

Auto-regulatory feedback by RNA-binding proteins

M Müller-McNicoll, O Rossbach, J Hui… - Journal of molecular …, 2019 - academic.oup.com
… -regulatory feedback by directly binding to and influencing the fate of their own mRNAs, exerting
control … For this feedback control, RBPs employ a variety of mechanisms operating at all …

Lessons from studying the AU-rich elements in chronic inflammation and autoimmunity

N Lourou, M Gavriilidis, DL Kontoyiannis - Journal of Autoimmunity, 2019 - Elsevier
… others to destine RNAs towards different fates. The development … RNA binding proteins; it
is ubiquitously expressed and binds to … The more details we learn about cross-talk, molecular …

Multiple roles for AU-rich RNA binding proteins in the development of haematologic malignancies and their resistance to chemotherapy

P Podszywalow-Bartnicka, KM Neugebauer - RNA biology, 2024 - Taylor & Francis
… of RBPs that bind to AU-rich elements (AREs) within mRNAs. … illustrate how RNA binding
proteins orchestrate the fate of … crucial role of AU-rich element-mediated control. Additionally, …

RNA-binding proteins as important regulators of long non-coding RNAs in cancer

K Jonas, GA Calin, M Pichler - International journal of molecular sciences, 2020 - mdpi.com
… the binding of RNA decay-promoting proteins to these AU-rich … The post-transcriptional
regulation of mRNA by AUF1 is … in order to regulate the destiny and function of a target lncRNA. …

Post-translational control of RNA-binding proteins and disease-related dysregulation

A Velázquez-Cruz, B Baños-Jaime… - Frontiers in molecular …, 2021 - frontiersin.org
… The cross-talk between RBPs is an essential part of the … fate. In the canonical miRNA
biogenesis pathway, immature … For example, HuR binds to AU-rich elements (ARE) in the 3′ …

Post-transcriptional gene regulatory networks in chronic airway inflammation: role of RNA-binding proteins

L Ricciardi - 2020 - elea.unisa.it
Crosstalk between RBPs will be further discussed in … for AU-rich sequences in mRNAs. This
is due to the combination … In conclusion, the fate of an ARE-bearing transcript targetable by …

RNA-binding proteins in the control of LPS-induced macrophage response

DH Ostareck, A Ostareck-Lederer - Frontiers in genetics, 2019 - frontiersin.org
… on their target mRNAs, which are regulated at the level of mRNA stability and translation in
… Specific RBPs, TTP, HUR, TIAR, and hnRNP K, regulate the fate of their cellular target RNAs