… remodeling and increased cell activation. Trivalent CAR T cells … the antigen receptor, provide
the inhibitory signal, and allow the possibility to regulate the strength of this inhibitory signal…

… signaling, inflammation, and serves as a negative regulator … B-cell activation thresholds
via B-cell receptor-dependent and … that B7-H3 serves as an inhibitor to T-cell cytotoxicity and …

… BCR activation in GCB DLBCL, we recently investigated the expression of several negative
regulators … Beside infection, chronic antigen stimulation in the context of certain autoimmune …

… T1D is due to autoimmune β cell destruction, usually … T cell activation: the HLA-DR molecules
present autoantigens to T cells, PTPN22 negatively influences the T cell receptor signaling …

… B cell activating factor (BAFF) acts as a survival factor for … autoimmunity by functioning as
a negative regulator of T cell … CD4 T cell expansion and Th1 function, and inhibited TGFβ-…

… in DLBCL and MCL and will cover both approved inhibitors … supporting that several
autoimmune diseases are risk factors … ; loss of function mutations in A20 (a NF-κB negative …

… efficacy of DC and chimeric antigen receptor T-cell vaccines will be … pathways that ward off
autoimmunity during immune responses … We posit that blocking either regulator T cells or their …

… as prognostic tool in B cell lymphoma, autoimmune diseases and immune-mediated disorders,
… ) levels, thereby inhibiting the expression of the B-cell activation factor receptor (BAFF-R), …

… blocking of ERK1/2 activation. These signaling pathways are involved in the regulation of …
RAGE association with AGEs, HMGB1 and S100A9 protein in endothelial cell activate PI3K, …

… lymphocytes, the activation of class 1 PI3Ks is controlled by antigen receptor, co-stimulatory
receptors… effect of inhibiting both the PI3Kδ and PI3Kγ isoforms on autoimmune phenotypes …