The CD318/CD6 axis limits type 1 diabetes islet autoantigen-specific human T cell activation
J Do, D Arribas-Layton, J Juan, I Garcia… - … of Autoimmunity, 2024 - Elsevier
… Itolizumab has been shown to inhibit T cell activation and … whether the inhibitory effect of
CD318 on T cell activation is … mAb act synergistically to inhibit CD4 and CD8 T cell proliferation …
CD318 on T cell activation is … mAb act synergistically to inhibit CD4 and CD8 T cell proliferation …
PI3Kδ/γ inhibition promotes human CART cell epigenetic and metabolic reprogramming to enhance antitumor cytotoxicity
CR Funk, S Wang, KZ Chen, A Waller… - Blood, The Journal …, 2022 - ashpublications.org
… Current limitations in using chimeric antigen receptor T(CART… –mediated autoimmunity, we
studied the effects of inhibiting … 45% of patients with CLL of Rai stages 0 and 1 exceeded this …
studied the effects of inhibiting … 45% of patients with CLL of Rai stages 0 and 1 exceeded this …
B cell-T cell interplay in immune regulation: A focus on follicular regulatory T and regulatory B cell functions
D Tan, W Yin, F Guan, W Zeng, P Lee… - Frontiers in Cell and …, 2022 - frontiersin.org
… In our opinion, Particular autoimmune models and … ) ligand 9(CXCL9) and B cell activating
factor (BAFF) from B cells … to Tregs with chimeric antigen receptor (CAR)technology, providing …
factor (BAFF) from B cells … to Tregs with chimeric antigen receptor (CAR)technology, providing …
Serotonin: a potent immune cell modulator in autoimmune diseases
M Wan, L Ding, D Wang, J Han, P Gao - Frontiers in immunology, 2020 - frontiersin.org
… activating 5-HT 2B receptors, whereas dermal thickening was found to be attenuated with
5-HT 2B receptor signaling pathway inhibitors (… or its signaling pathway is inhibited in the CNS. …
5-HT 2B receptor signaling pathway inhibitors (… or its signaling pathway is inhibited in the CNS. …
IFN-induced protein with tetratricopeptide repeats 2 (Ifit2) limits autoimmune inflammation by regulating myeloid cell activation and metabolic activity
D Kim, NK Rai, A Burrows, S Kim, A Tripathi… - bioRxiv, 2022 - biorxiv.org
… and is being widely used to treat certain autoimmune conditions, such as multiple sclerosis
(… function of Ifit2 in autoimmune inflammation in part by modulating myeloid cell function and …
(… function of Ifit2 in autoimmune inflammation in part by modulating myeloid cell function and …
[HTML][HTML] Self-DNA at the epicenter of SLE: immunogenic forms, regulation, and effects
C Soni, B Reizis - Frontiers in Immunology, 2019 - frontiersin.org
… STING functions as a negative regulator of endosomal TLR … /TLR–dual signaling in
autoimmune B cell responses was … IFNα signaling positively correlated with B cell activation and …
autoimmune B cell responses was … IFNα signaling positively correlated with B cell activation and …
P66Shc: a pleiotropic regulator of B cell trafficking and a gatekeeper in chronic lymphocytic leukemia
L Patrussi, N Capitani, CT Baldari - Cancers, 2020 - mdpi.com
… as a negative regulator of antigen receptor signaling has … systemic lupus-like autoimmune
disease characterized by … In addition to the widely used Rai-Binet clinical staging systems [65], …
disease characterized by … In addition to the widely used Rai-Binet clinical staging systems [65], …
Insights on the role of anti-inflammatory and immunosuppressive agents in the amelioration of diabetes
… autoimmune process is the regulation and control of local inflammatory cytokines production.
The deteriorating effects of autoimmune … of insulin signaling through the inhibition of IRS-1 …
The deteriorating effects of autoimmune … of insulin signaling through the inhibition of IRS-1 …
Autoimmunity and Carcinogenesis: Their Relationship under the Umbrella of Autophagy
G Műzes, F Sipos - Biomedicines, 2023 - mdpi.com
… degrades a negative regulator of Fas-induced apoptosis that is cell type-specific. … autoimmune
disorders; however, reducing the value for T cell activation may enhance tumor inhibition …
disorders; however, reducing the value for T cell activation may enhance tumor inhibition …
[PDF][PDF] Lymphopenia-induced lymphoproliferation drives activation of naive T cells and expansion of regulatory populations
… Thus, human LIP response is characterized by cytokine and TCR-driven proliferation which
drives global T cell activation but also preferentially triggers regulatory cell expansion which …
drives global T cell activation but also preferentially triggers regulatory cell expansion which …