Raman fingerprints as promising markers of cellular senescence and aging

L Liendl, J Grillari, M Schosserer - GeroScience, 2020 - Springer
… A typical Raman spectrum of mammalian cells is shown. … Raman spectra from biological
materials, typically recorded in the … model trained with proliferating and senescent cells grown in …

The emerging role of Raman spectroscopy as an omics approach for metabolic profiling and biomarker detection toward precision medicine

G Cutshaw, S Uthaman, N Hassan… - Chemical …, 2023 - ACS Publications
… where the intrinsic Raman scattering of biological materials is … play key roles in cancer
cell proliferation, where amino acids … (b) (left) Raman spectra of five selected cell lines (averaged …

Spectroscopic label-free microscopy of changes in live cell chromatin and biochemical composition in transplantable organoids

G Pettinato, MF Coughlan, X Zhang, L Chen… - Science …, 2021 - science.org
… high amounts that are normally observed in cell cultures (Fig. 2O). … biochemical changes,
we also used Raman spectroscopy to … cell proliferation toward oncogenesis (76). As an optical …

Probing metabolic alterations in breast cancer in response to molecular inhibitors with Raman spectroscopy and validated with mass spectrometry

X Wen, YC Ou, G Bogatcheva, G Thomas… - Chemical …, 2020 - pubs.rsc.org
… -PET is primarily due to its ability to only visualize changes in … Spectra were normalized to
1440 cm −1 biological peak. The … types and activate cancer cells proliferation and survival. The …

[PDF][PDF] DEVELOPMENT OF A LABEL-FREE DETECTION TECHNIQUE FOR HUMAN INFECTIOUS VIRUS BY RAMAN SPECTROSCOPY

K Moor - 2020 - kwansei.repo.nii.ac.jp
… and detected the cellular reaction due to virus invasion three … virus cannot proliferate in
normal human cells that lack this … culture dish may cause contamination of the cell culture. The …

Overview of optical and electrochemical alkaline phosphatase (ALP) biosensors: Recent approaches in cells culture techniques

T Balbaied, E Moore - Biosensors, 2019 - mdpi.com
… from proliferation to differentiation in colon cell lines; Caco-2 cells [43]. … methodologies for
ALP detection in biological samples. For … Raman spectroscopy is based on the light scattering

[HTML][HTML] Redox state changes of mitochondrial cytochromes in brain and breast cancers by Raman spectroscopy and imaging

H Abramczyk, JM Surmacki, B Brozek-Pluska - Journal of Molecular …, 2022 - Elsevier
… , and proliferation we need new tools to monitor biochemistry, … in normal and cancer cells
may be related to the protein … 1582 cm −1 for cancerous cell lines (CRL1718, U87MG and Daoy…

Raman spectroscopy assisted biochemical evaluation of L929 fibroblast cells on differentially crosslinked gelatin hydrogels

G Kulkarni, PG Ray, S Das, S Biswas, S Dhara… - … Spectroscopy, 2021 - Elsevier
… possesses limitations due to dye entrapment. In contrast, … to understand the status of L929
fibroblast cells cultured on … from Raman spectroscopy, we sought to perform cell proliferation

Evaluation of label-free confocal Raman microspectroscopy for monitoring oxidative stress in vitro in live Human cancer cells

JM Surmacki, I Quiros-Gonzalez, SE Bohndiek - Antioxidants, 2022 - mdpi.com
Raman spectroscopy to monitor redox biochemical changes in … metabolism and proliferation
of cancer cells, combined with … here that Raman spectroscopy is able to detect the effects of …

Biomolecular phenotyping and heterogeneity assessment of mesenchymal stromal cells using label-free Raman spectroscopy

RA Rocha, JM Fox, PG Genever, Y Hancock - Scientific Reports, 2021 - nature.com
… Y102/Y202 due to these groups having previously defined, … individual cell-lines and those
with shared biological features … cell-type, with a sub-set that fully distinguishes the cell lines. …