[HTML][HTML] Triple artemisinin-based combination therapies versus artemisinin-based combination therapies for uncomplicated Plasmodium falciparum malaria: a …

RW van Der Pluijm, R Tripura, RM Hoglund, AP Phyo… - The Lancet, 2020 - thelancet.com
… to malaria control and elimination. Triple artemisinin-based combination therapies (TACTs), …
, might provide effective treatment and delay emergence of antimalarial drug resistance. …

Triple artemisinin-based combination therapies for malaria: proceed with caution–Authors' reply

RW van der Pluijm, AP Phyo, D Lek, NJ White… - The Lancet, 2020 - thelancet.com
… of an individual drug in clinical trials, the more difficult it is to … in the combination group (group
A), will this regimen be practice-… is shown to be better (or not) than sequential therapy can a …

[HTML][HTML] … treatment of malaria with artemisinin-based combination therapies among schoolchildren in Mali: a three-group open label randomized controlled trial

H Maiga, C Opondo, RM Chico, LM Cohee… - The American Journal …, 2022 - ncbi.nlm.nih.gov
… were assigned a study number in the sequence of presentation within their … , treatment was
readministered. Children returned the following 2 days to complete their respective regimens. …

[HTML][HTML] Artemisinin-based combination therapy for uncomplicated Plasmodium falciparum malaria in Mali: a systematic review and meta-analysis

FO Maiga, M Wele, SM Toure, M Keita, CO Tangara… - Malaria Journal, 2021 - Springer
… standard regimens showed high success rates against both … : selection bias (random
sequence generation and allocation … out clinical trials or high-quality observational studies that …

[HTML][HTML] Pharmacokinetics/pharmacodynamics of chloroquine and artemisinin-based combination therapy with primaquine

A Daher, G Aljayyoussi, D Pereira, MVG Lacerda… - Malaria Journal, 2019 - Springer
… efficacy of these three treatment regimens and the influence of … enrolled in a larger clinical
trial previously published and … ultrasensitive PCR of all consecutive samples of the patients …

[HTML][HTML] … five-arm, non-inferiority, individually randomized controlled trial of the efficacy and safety of praziquantel plus artemisinin-based combinations in the treatment …

CO Obonyo, VO Were, P Wamae, EMO Muok - Trials, 2023 - Springer
… four artemisinin-based combination therapies (4 mg/kg of the artemisinin component, once a
day for three consecutive … A copy of the treatment sheet with dosing regimens is provided as …

[HTML][HTML] Preventing antimalarial drug resistance with triple artemisinin-based combination therapies

TD Nguyen, B Gao, C Amaratunga, M Dhorda… - Nature …, 2023 - nature.com
Randomized clinical trials in Asia with dihydroartemisinin-… AL is the only regimen to select
strongly for N86, although this … model simulations, by successive acquisition of the pfkelch13 …

[HTML][HTML] Triple artemisinin-based combination therapies for malaria–a new paradigm?

RW van der Pluijm, C Amaratunga, M Dhorda… - Trends in …, 2021 - cell.com
… resulted in high failure rates of artemisinin-based combination therapies (ACTs) in the GMS.
… to malaria control. Triple ACTs (TACTs), combining an artemisinin and two existing partner …

[PDF][PDF] A multi-centre randomised controlled non-inferiority trial to compare the efficacy, safety and tolerability of Triple Artemisinin-based Combination Therapies …

AM Dondorp, NJ White, NPJ Day, MJ Dhorda… - cdn.clinicaltrials.gov
… Appendix 2 for dosing regimens … Therefore, we aim to conduct a large scale randomized
clinical trial in up to 8 … a combination of both study drugs boxes will be sequentially numbered. …

[HTML][HTML] A randomized controlled trial of dihydroartemisinin-piperaquine, artesunate-mefloquine and extended artemether-lumefantrine treatments for malaria in …

M Saito, VI Carrara, ME Gilder, AM Min, NW Tun… - BMC medicine, 2021 - Springer
… Artemisinin and artemisinin-based combination therapy (ACT… lumefantrine regimen has been
associated with high treatmentsequentially numbered opaque envelopes kept at each trial