Efficacy and harms of longterm opioid therapy in chronic noncancer pain: Systematic review and meta‐analysis of open‐label extension trials with a study duration …

P Bialas, C Maier, P Klose… - European Journal of Pain, 2020 - Wiley Online Library
long-term opioid therapy (LTOT) for chronic non-cancer pain (… randomized trial of patients
on study medication at the end of … One study tested morphine (maximum dosage 90 mg/day, …

[HTML][HTML] Comparative benefits and harms of individual opioids for chronic non-cancer pain: a systematic review and network meta-analysis of randomised trials

A Noori, B Sadeghirad, L Wang… - British journal of …, 2022 - Elsevier
chronic non-cancer pain (pain lasting at least 3 months), randomised them to receive different
opioids (oral… + paracetamol, morphine + acetaminophen), and trials or trial arms of opioids …

Efficacy of interventions to reduce long term opioid treatment for chronic non-cancer pain: systematic review and meta-analysis

N Avery, AG McNeilage, F Stanaway… - Bmj, 2022 - bmj.com
… Opioid overprescribing for patients with chronic non-cancer painRandomized trial of sacroiliac
joint arthrodesis compared … intrathecal morphine delivery in chronic noncancer pain. BMJ …

… for chronic noncancer neuropathic pain. An updated systematic review and meta‐analysis of efficacy, tolerability and safety in randomized placebo‐controlled studies …

C Sommer, P Klose, P Welsch, F Petzke… - … Journal of Pain, 2020 - Wiley Online Library
… The average dosages reported for morphine, oxycdone and tramadol in the studies … German
guidelines group on long-term opioid therapy for chronic non-cancer pain. CS has received …

The effects of longterm opioid treatment on the immune system in chronic noncancer pain patients: A systematic review

PDK Diasso, H Birke, SD Nielsen… - … Journal of Pain, 2020 - Wiley Online Library
chronic non-cancer pain (CNCP). An association between … be obtained) and one randomized
controlled trial (RCT) and … CNCP patients after 30 days of oral morphine treatment (n = 11…

High‐dose opioids for chronic noncancer pain: an overview of Cochrane Reviews

C Els, TD Jackson, R Hagtvedt, D Kunyk… - Cochrane Database …, 2023 - cochranelibrary.com
Chronic noncancer pain (CNCP) is any chronic pain that is … Opioids are a type of pain
medicine related to morphine. … with a lower risk of bias than non‐randomised study designs. …

People with chronic non-cancer pain receiving chronic morphine treatment at the Chronic Pain Management Clinic of Groote Schuur Hospital: a cross-sectional survey …

P Moodley - 2023 - open.uct.ac.za
… use of chronic opioids for the treatment of chronic non-cancer pain is controversial … study,
we assessed the characteristics of chronic non-cancer pain patients attending the Chronic Pain

Intrathecal delivery of hydromorphone vs morphine for refractory cancer pain: a multicenter, randomized, single-blind, controlled noninferiority trial

K Ma, Y Jin, L Wang, ZY Feng, T Song, XQ Yang… - Pain, 2020 - journals.lww.com
… after IT bolus infusion, which is in line with the need for rapid onset of PCA, and explains
the advantages of hydromorphone over morphine in controlling BTP, as observed in our study. …

Longterm opioid treatment and endocrine measures in chronic noncancer pain patients: A systematic review and meta‐analysis

PDK Diasso, BS Frederiksen, SD Nielsen… - … Journal of Pain, 2021 - Wiley Online Library
… finally thirteen studies (one randomized controlled trial (RCT), … adrenal axis in adult chronic
non-cancer pain patients. This … Daily opioid dose varied from 10 to 400 mg oral morphine

Does opioid therapy enhance quality of life in patients suffering from chronic non-malignant pain? A systematic review and meta-analysis

KVL Kraft, T Backmund, L Eberhart… - … Journal of Pain, 2024 - journals.sagepub.com
… or secondary outcome, S (study design): randomized controlled trials. The PICOS scheme 39
… While our main emphasis was on general insights into chronic non-cancer pain and HRQL, …