Immunogenicity and safety of meningococcal group A, C, W and Y tetanus toxoid conjugate vaccine: review of clinical and real-world evidence

J Findlow, M Knuf - Future Microbiology, 2019 - Taylor & Francis
reactogenicity and safety after primary and booster MenACWY-TT vaccination in all age groups
[Citation13]. Reactogenicity in … Reactogenicity profiles were also similar after booster and …

[HTML][HTML] Use of tetanus-diphtheria (Td) vaccine in children 4–7 years of age: World Health Organization consultation of experts

S Desai, HM Scobie, T Cherian, T Goodman… - Vaccine, 2020 - Elsevier
… , (4) less reactogenicity compared with use of full-dose diphtheria vaccine, potentially improving
the … evidence on immunogenicity and safety of Td vaccine use in 4–7 year old children. …

New pertussis vaccines: a need and a challenge

D Hozbor - Pertussis Infection and Vaccines: Advances in …, 2019 - Springer
reduced the morbidity and mortality associated with pertussis. Because of reports on the
induction of adverse reactions, less-reactogenic acellular … on their aforementioned immunogenic

Current challenges and improvements in assessing the immunogenicity of bacterial vaccines

G Fantoni, G Boccadifuoco, F Verdirosa… - Frontiers in …, 2024 - frontiersin.org
… the continuous discovery of immunogenic epitopes. Bacteria possess a variety of antigens
whose immunogenic potential is often unknown, and it is unclear which antigen can elicit a …

Immunogenicity and reactogenicity in Q fever vaccine development

AP Fratzke, EJ van Schaik, JE Samuel - Frontiers in Immunology, 2022 - frontiersin.org
… to the severity of reactogenic responses associated with it. This reactogenicity continues to
be a … burnetii vaccines, our knowledge of immunogenicity and reactogenicity in C. burnetii …

[HTML][HTML] Safety and immunogenicity of the epicutaneous reactivation of pertussis toxin immunity in healthy adults: a phase I, randomized, double-blind, placebo …

O Chatzis, G Blanchard-Rohner, L Mondoulet… - Clinical Microbiology …, 2021 - Elsevier
… period; reactogenicity events were solicited through day 42. … that antigen delivery was limited
by specific characteristics of human adult skin. Indeed, human skin has lower water content, …

Pertussis toxin neutralizing antibody response after an acellular booster vaccination in Dutch and Finnish participants of different age groups

A Knuutila, P Versteegen, AM Barkoff… - Emerging Microbes & …, 2022 - Taylor & Francis
… , widespread vaccination of young children has reduced the incidence of pertussis. However,
due to the high reactogenicity of wPvs, acellular pertussis vaccines (aPv) were developed …

Diphtheria, tetanus, and pertussis immunization in children 6 weeks through 6 years of age

JE Drutz, JA Boom, MS Edwards - … . com/contents/diphtheria-tetanus …, 2019 - uptodate.com
… When used as protein conjugates, these toxoids do not substitute for diphtheria or tetanus
toxoid immunization because they are not sufficiently immunogenic [8,9]. However, as vaccine …

Safety and effectiveness of acellular pertussis vaccination during pregnancy: a systematic review

S Vygen-Bonnet, W Hellenbrand, E Garbe… - BMC infectious …, 2020 - Springer
… The majority of pregnant women has low concentrations of pertussis-specific antibodies
and thus newborns are insufficiently protected by maternally transferred antibodies. Acellular

Evaluating the Compatibility of New Recombinant Protein Antigens (Trivalent NRRV) with a Mock Pentavalent Combination Vaccine Containing Whole-Cell Pertussis …

P Kumar, DA Holland, K Secrist, P Taskar, B Dotson… - Vaccines, 2024 - mdpi.com
reactogenicity profile of this vaccine has been improved by replacing wP with aP (acellular
pertussis) antigens, … The mouse immunogenicity assay was used in this work to evaluate the …