Sequencing and chromosome-scale assembly of the giant Pleurodeles waltl genome

T Brown, A Elewa, S Iarovenko, E Subramanian… - BioRxiv, 2022 - biorxiv.org
… Here, we leveraged advanced long-read and chromosome … waltl genome of relevance to
regeneration research and … with the Tig1 locus in the indicated tetrapod species. Genes are …

A comprehensive reference transcriptome resource for the Iberian ribbed newt Pleurodeles waltl, an emerging model for developmental and regeneration biology

M Matsunami, M Suzuki, Y Haramoto, A Fukui… - DNA …, 2019 - academic.oup.com
properties, notably including prominent regeneration ability. The Iberian ribbed newt, Pleurodeles
waltl, … genome editing methods. However, limited genetic information is available for P. …

Efficient Gene Disruption via Base Editing Induced Stop in Newt Pleurodeles waltl

H Cai, Z Peng, R Ren, H Wang - Genes, 2019 - mdpi.com
… the possibility of base editing in salamanders by using the induction of stop codons (iSTOP)
knockout strategy in the Iberian ribbed newt (Pleurodeles waltl). The gene inactivation is …

Molecular Signatures Integral to Natural Reprogramming in the Pigment Epithelium Cells after Retinal Detachment in Pleurodeles waltl

Y Markitantova, A Fokin, D Boguslavsky… - International Journal of …, 2023 - mdpi.com
Gene expression profiling reveals the regeneration-specific molecular activities of RPE cells
during reprogramming after the retinal detachment (4 days and 7 days po). A total of 1003 …

Fgf10 mutant newts can regenerate normal limbs despite severe developmental hindlimb defects

M Suzuki, A Okumura, Y Shibata, T Endo, M Teramoto… - bioRxiv, 2023 - biorxiv.org
… broadly conserved in tetrapods and/or involved in adult limb regeneration remains unknown…
line in the newt Pleurodeles waltl which have amazing regenerative ability. While Fgf10 …

Model systems for regeneration: salamanders

A Joven, A Elewa, A Simon - Development, 2019 - journals.biologists.com
Pleurodeles offer two accessible systems in which genome … as between salamanders and
less regenerative tetrapods. … , including that of long-read technologies such as PacBio and …

Appendage regeneration in vertebrates: what makes this possible?

V Daponte, P Tylzanowski, A Forlino - Cells, 2021 - mdpi.com
regenerative studies. Recently, a newt model (Pleurodeles waltl), sharing the same regeneration
… Zebrafish msxb/msxc genes, related to Msx genes of tetrapods [205], are upregulated …

CRISPR-Cas9-Based Functional Analysis in Amphibians: Xenopus laevis, Xenopus tropicalis, and Pleurodeles waltl

M Suzuki, M Iida, T Hayashi, KT Suzuki - Genome Editing in Animals …, 2023 - Springer
… cost compared to other tetrapod model organisms and with … [12] and has full regeneration
capacity throughout its life in … “Reading” a genome by NGS and “editing” it by CRISPR-Cas …

[PDF][PDF] The West African lungfish provides insights into the evolution of tetrapod tail regeneration

KM Verissimo, LN Perez, AC Dragalzew… - Proc Biol Sci, 2020 - academia.edu
… tail stages (1 dpa and 21 dpa) showed high variation in read counts among replicas and …
genome [44]. This was also shown to be the case in the Iberian ribbed newt Pleurodeles waltl […

Salamander-like tail regeneration in the West African lungfish

KM Verissimo, LN Perez… - … of the Royal …, 2020 - royalsocietypublishing.org
… molecular hallmarks of tetrapod tail regeneration in the West … For each run, all read datasets
were mapped to reference … [50], the Iberian ribbed newt Pleurodeles waltl [51], the axolotl […