Pathogenesis, clinical features of asthma COPD overlap, and therapeutic modalities

S Dey, MS Eapen, C Chia… - … of Physiology-Lung …, 2022 - journals.physiology.org
… The asthma COPD overlap (ACO) is not a single … and clinical features consistent with
asthma and COPD. The ACO phenotype has been a matter of immense concern as most clinical

Mechanisms, pathophysiology and currently proposed treatments of chronic obstructive pulmonary disease

SO Rodrigues, CMC Cunha, GMV Soares, PL Silva… - Pharmaceuticals, 2021 - mdpi.com
COPD pathophysiology, and provides an update on the development and clinical testing of
novel COPD … section, we discuss both immune and structural cells in COPD pathophysiology. …

COPD 2020: changes and challenges

A Agustí, C Vogelmeier… - … of Physiology-Lung …, 2020 - journals.physiology.org
… According to this model, COPD was a self-… lung function decline with age (22). Until recently,
this model has constituted the “holy grail” of our understanding of the pathogenesis of COPD

The pathology of small airways disease in COPD: historical aspects and future directions

A Higham, AM Quinn, JED Cançado, D Singh - Respiratory research, 2019 - Springer
… a comprehensive review of the pathology of SAD in COPD. We give a … in COPD, and
describe the various pathological features of SAD. We focus on clinically relevant topics, including

Recent advances in chronic obstructive pulmonary disease pathogenesis: from disease mechanisms to precision medicine

CA Brandsma, M Van den Berge… - … of pathology, 2020 - Wiley Online Library
features of COPD pathology, has been very important for the study of disease mechanisms
in COPD … individual differences in the disease pathology of COPD and are important to …

COPD pathogenesis: finding the common in the complex

JO Cantor, GM Turino - Chest, 2019 - Elsevier
… with the recognition that physiological disorders result from a … to the lung, computer simulations
of pulmonary emphysema … those seen in pulmonary fibrosis and emphysema, respectively…

[HTML][HTML] Physiology, lung

M Haddad, S Sharma - 2019 - europepmc.org
COPD is one of the major leading causes of lung pathology worldwide. … basic lung physiology
and its ties to pathology is essential for the clinician. Dysfunction of the pulmonary system

[HTML][HTML] Pathobiological mechanisms underlying metabolic syndrome (MetS) in chronic obstructive pulmonary disease (COPD): clinical significance and therapeutic …

SMH Chan, S Selemidis, S Bozinovski… - Pharmacology & …, 2019 - Elsevier
… of the progressive lung pathology in COPD patients. As MetS has important clinical implications
on COPD outcomes, identification of disease mechanisms linking COPD to MetS is the …

COVID-19, COPD, and AECOPD: immunological, epidemiological, and clinical aspects

F Polverino, F Kheradmand - Frontiers in Medicine, 2021 - frontiersin.org
COPD and analyze the pathobiological and clinical features of … common pathobiological and
clinical features with other viral … , our understanding of the pathophysiology and treatment of …

Hypercapnia in COPD: causes, consequences, and therapy

B Csoma, MR Vulpi, S Dragonieri, A Bentley… - Journal of Clinical …, 2022 - mdpi.com
Pulmonary hyperinflation plays a central role in the pathogenesis of hypercapnia in COPD
[… recovery of the respiratory system and leading to improvement in lung function parameters, …