Nanoparticlemediated siRNA delivery systems for cancer therapy

H Gao, R Cheng, H A. Santos - View, 2021 - Wiley Online Library
… nanoparticles applied for siRNA delivery with effective formulations both in vitro and in vivo.
… the advanced developments on nanocarriers for siRNA delivery, with multiple options on …

Nanoparticlemediated siRNA delivery and multifunctional modification strategies for effective cancer therapy

M Chen, C Dong, S Shi - Advanced Materials Technologies, 2021 - Wiley Online Library
… Monofunctional nanoparticle-mediated siRNA delivery can usually only achieve a single
treatment mode, while multifunctional nanoparticle-mediated siRNA delivery combined with …

Lipid nanoparticle-mediated siRNA delivery for safe targeting of human CML in vivo

N Jyotsana, A Sharma, A Chaturvedi, R Budida… - Annals of …, 2019 - Springer
… and non-toxic delivery of siRNA in vitro and in vivo with nearly 100% uptake of LNP-siRNA
By testing and validating the safety and functional efficacy of LNP-mediated siRNA delivery

Iron Oxide Nanoparticle-Mediated siRNA Delivery System for Huntington's Disease Treatment

SS Rohiwal, TD Nguyen, E Kamenna… - ACS Applied Nano …, 2023 - ACS Publications
… Thus, these MNPs may represent a promising and efficient platform for siRNA delivery and
… underneath the cells for 3 h during in vitro siRNA delivery. The cells were incubated for 9 h …

Charge-reversible lipid derivative: A novel type of pH-responsive lipid for nanoparticle-mediated siRNA delivery

Y Hirai, R Saeki, F Song, H Koide, N Fukata… - International journal of …, 2020 - Elsevier
… Lipid nanoparticles (LNP) composed of ionizable lipids and siRNA are known as a leading
siRNA delivery system. However, LNPs composed of conventional ionizable lipids will be …

VEGF overexpression significantly increases nanoparticle-mediated siRNA delivery and target-gene downregulation

S Tan, Z Chen, Y Mironchik, N Mori, MF Penet, G Si… - Pharmaceutics, 2022 - mdpi.com
… effective siRNA delivery and downregulation of the target gene Chkα and its function. …
increased vascularization on Chkα siRNA delivery and the target-gene functional outcome. …

Recent advances in treatment of lung cancer: Nanoparticle-based drug and siRNA delivery systems

A Gencer, C Duraloglu, S Ozbay, TT Ciftci… - … drug delivery, 2021 - ingentaconnect.com
… based siRNA delivery system was conducted with B16F10 mice, and the PEI-WT1 siRNA
complexes … with nanoparticle-mediated CDK4 siRNA delivery. Mol. Ther., 2014, 22(5), 964-973. …

Nanoparticle mediated RNA delivery for wound healing

E Kolanthai, Y Fu, U Kumar, B Babu… - Wiley …, 2022 - Wiley Online Library
… includes continuous delivery of siRNA and targeting miRNA. siRNA delivery and targeting
… miRNA/siRNA assisted wound healing can benefit from the advancements in viral vector …

Nanoparticlemediated double‐stranded RNA delivery system: A promising approach for sustainable pest management

S Yan, BY Ren, J Shen - Insect Science, 2021 - Wiley Online Library
… for nucleic acid delivery in insects (Zhang et al., 2015c; Zhang et al., 2015d; Kim et al.,
2018). The process and mechanism of nanoparticle-mediated dsRNA/siRNA delivery can be …

Nanoparticle-mediated delivery of siRNA into zebrafish heart: a cell-level investigation on the biodistribution and gene silencing effects

F Wang, X Wang, L Gao, LY Meng, JM Xie, JW Xiong… - Nanoscale, 2019 - pubs.rsc.org
… and had functional effects for siRNA delivery. With similar physiochemical characteristics …
P–P–R 9 based siRNA nanoparticles would also be safe and efficient for siRNA delivery in the …