Association of FBN1 polymorphism with susceptibility of adolescent idiopathic scoliosis: a case-control study

GBL De Azevedo, JA Perini, AEP Araújo Junior… - BMC Musculoskeletal …, 2022 - Springer
… (AIS), a three-dimensional deformity of the spine, typically becomes evident near the onset
of puberty, with no apparent cause and prevalence around 3% [1]. Most patients have non-…

3D deformation patterns of S shaped elastic rods as a pathogenesis model for spinal deformity in adolescent idiopathic scoliosis

S Pasha - Scientific reports, 2019 - nature.com
… The primary cause of scoliosis remains unknown. The lack of such understanding has
hampered development of effective preventive methods for management of this disease. A long-…

Evaluation of choroidal changes in adolescent idiopathic scoliosis using enhanced depth imaging optical coherence tomography

DM Ulusoy, S Akkaya, S Batın - Clinical and Experimental …, 2020 - Taylor & Francis
… Citation2013 The cause of AIS seems to be multifactorial and no isolated factor has been …
lower melatonin levels are attributed as the cause for disease development.Citation2016 …

Novel mutations in UTS2R are associated with adolescent idiopathic scoliosis in the Chinese population

Z Dai, Y Wang, Z Wu, Z Feng, Z Liu, Y Qiu, JCY Cheng… - Spine, 2021 - journals.lww.com
… Furthermore, mutations in urotensin II receptor (UTS2R) were reported to cause severe
scoliosis in zebrafish. In spite of the evidence presented in animal models, there is still a lack of …

How common is back pain and what biopsychosocial factors are associated with back pain in patients with adolescent idiopathic scoliosis?

AYL Wong, D Samartzis, PWH Cheung… - Clinical Orthopaedics …, 2019 - journals.lww.com
… Although it is known that back pain can cause functional limitations in adolescents, the
current study found that these young individuals with back pain were experiencing insomnia and …

Spinal orthosis in adolescent idiopathic scoliosis: an overview of the braces provided by the National Health Service in Italy

CM Del Prete, D Tarantino, MG Viva, M Murgia… - Medicina, 2023 - mdpi.com
… The diagnosis of AIS is defined when other causes of scoliosis, such as neuromuscular
diseases, syndromes, and malformations of the spine, have been excluded [1,8,9]. Adam’s …

The susceptibility and potential functions of the LBX1 gene in adolescent idiopathic Scoliosis

M Luo, Y Zhang, S Huang, Y Song - Frontiers in Genetics, 2021 - frontiersin.org
… susceptibility genes for adolescent idiopathic scoliosis (AIS). … LBX1 is the most promising
candidate gene in the etiology of … into the potential role of the LBX1 gene in the etiology of AIS. …

Single Nucleotide Polymorphisms and Adolescent Idiopathic Scoliosis: A Systematic Review and Meta-Analysis of the Literature

AK AlMekkawi, JP Caruso, TY El Ahmadieh… - Spine, 2023 - journals.lww.com
Adolescent idiopathic scoliosis (AIS) is considered one of the most prevalent spinal diseases.
Even though the cause of … is similarly affected, indicating a possible genetic etiology to AIS. …

… -related quality of life and postural changes of spinal alignment in female adolescents associated with back pain in adolescent idiopathic scoliosis: a prospective cross …

T Makino, T Kaito, Y Sakai, S Takenaka, H Yoshikawa - Spine, 2019 - journals.lww.com
… No reports can be found on the association between AVT and back pain in AIS, though
we speculate that the dynamic changes of AVT at MT curve may cause mechanical stress for …

RHOA inhibits chondrogenic differentiation of mesenchymal stem cells in adolescent idiopathic scoliosis

M Yang, K Chen, C Hou, Y Yang, X Zhai… - Connective Tissue …, 2022 - Taylor & Francis
… The etiology of adolescent idiopathic scoliosis (AIS) remains unclear. The chondrogenic
differentiation of mesenchymal stem cells (MSCs) is important in AIS, and the Ras homolog …