Design, synthesis and anticancer evaluation of β-carboline-1-one hydantoins

CH Yao, TC Hsieh, JS Song, JC Lee - Future Medicinal Chemistry, 2020 - Future Science
studies of their biological activities have yet to be reported. … A solution of β-carbolin-1-one
thiohydantoin 5a (105 mg, 0.24 … , we studied their related structureactivity relationship by the …

Development in the Synthesis and Biological Activities of THβ-carboline and Its Analogs

N Bejigo, AM Yadessa - … of Science and Sustainable Development, 2022 - 213.55.101.19
… review summarizes the development in synthetic methods of THβCs and their comprehensive
biological activities over the … The SAR studies have demonstrated that the introduction of …

Synthesis and biological evaluation of marine alkaloid-oriented β-carboline analogues

T Xu, L Shi, Y Zhang, K Wang, Z Yang, S Ke - European Journal of …, 2019 - Elsevier
… proven to exhibit diverse biological functions. During the course of our research for highly
active … were designed and synthesized, and their in vitro cytotoxic activities against SGC-7901, …

Recent Progress for the Synthesis of β-Carboline Derivatives–an Update

V Patel, T Bambharoliya, D Shah, Y Patel… - Polycyclic Aromatic …, 2024 - Taylor & Francis
pharmacological potentialities and their derivatives have attracted a great deal of interest due
to their wide range of biological activities. β-… The studies reveal that the synthetic strategies

Design, synthesis and bio-evaluation of C-1 alkylated tetrahydro-β-carboline derivatives as novel antifungal lead compounds

R Singh, A Jaisingh, IK Maurya, DB Salunke - Bioorganic & Medicinal …, 2020 - Elsevier
… to synthesize cis- and trans diastereomers to understand the effect of specific stereochemistry
on the biological activity. … Further SAR investigation on this lead compound to improve the …

Discovery of β-carboline-(phenylsulfonyl) furoxan hybrids as potential anti-breast cancer agents

X Hu, X Gao, G Gao, Y Wang, H Cao, D Li… - Bioorganic & Medicinal …, 2021 - Elsevier
strategy, and their inhibitory activities … in the biological activities. Furthermore, the compounds
(11g–j, 12g–j and 13g–j) linked with alkanolamine presented more potent inhibitory activity

Synthesis and Structure–Activity Relationships of 1-Aryl-β-carbolines as Affinity Probes for the 5-Hydroxytryptamine Receptor

CA Foley, YA Al-Issa, KP Hiller, SP Mulcahy - ACS Omega, 2019 - ACS Publications
… efforts into the synthesis and biological activity of these heterocycles by … -activity
relationship studies of CNS agents. Part 4: 2-[3-(4-aryl-1-piperazinyl)propyl]-1,2,3,4-tetrahydro-β-carbolin

Methodologies for the synthesis of β-carbolines

S Boswood, S Roesner - Targets in Heterocyclic Systems …, 2024 - researchonline.ljmu.ac.uk
… the structure activity relationship for this class of compounds. … Furthermore, the synthesis
and biological activity of TBHCs … tetrahydro-2-tosyl-9H-β-carbolin-4-ones 134, which could be …

Marine alkaloid pityriacitrin and its analogues: discovery, structures, synthetic methods and biological properties

S Ke, T Xu, Y Min, Z Wan, Z Yang… - Mini Reviews in …, 2021 - ingentaconnect.com
… the progress on the synthesis and biological activities of this … investigate the possible
structure-activity relationship for this … )-H of the aryl ring of aryl(β-carbolin-1yl)methanones has also …

1, 3-Disubstituted-tetrahydro-β-carbolines: A New Method for Stereochemical Assignment and Synthesis of Potential Antimalarial Agents

K Cagasova - 2021 - vtechworks.lib.vt.edu
… to the structure-activity relationship studies performed in our … promising improved biological
activity. Unfortunately, neither … biology and strategies to delay emergence and spread. Int. J. …