… B cell subsets including transitional cells originating from bone marrow, follicular and marginal
zone B cells, as well as B1 cells, … long-lived plasma cells), suggesting that at least one of …

… Here, we review current understanding of how B cell responses … -lived plasma cells, germinal
center cells, and memory cells; … Within the follicle, B cells migrate continuously along the …

… that regulate B cell differentiation to both promote long-lived … Therefore, in order for B cells
to transition into cellular Ig … in marginal zone B cells but not follicular B cells. This defect in …

… We discuss the regulatory effects of Tfr cells on B cell proliferation and the germinal center
response. … Then, we delve into the mechanisms that Tfr cells regulate GC B cells. Tfr …

… B cells are generally classified into B1 and B2 (follicular) B … and in at least one study as a
marker of B regulatory cells (47, … concentrate within the CD24++ CD38++ transitional B cells …

… plasma cell generation during the GC reaction is regulated for … region of the follicles, where
B cells proliferate extensively, … expression during the transition from B cells to plasma cells. …

… In contrast, other B cells will be programmed to return to the follicle and form a transient …
in methylation take place during the transition between germinal center and memory B …

… interaction with Tfh cells and follicular dendritic cells (FDCs) to select B cell clones with high
… , and has the lowest expression during the pro-B to pre-B cell transition [44, 45]. One key …

… cells directly select GC B cells to begin expressing Blimp-1, we found that expression of this
transcriptional regulator occurred even when follicular helper T cells … control mice. Numbers …

… located inside B-cell follicles within secondary … ), follicular dendritic cells (FDCs) that present
Ag in the form of immune complexes to GC B cells (3), and T follicular helper (Tfh) cells. CCs …