… Cannabis (marijuana) is a widely used drug for medical or … of the PI3K/AKT/GSK-3β/CREB
signaling pathway, it was … ), and CREB (Ser133) in four brain regions. The expression levels of …

… compound in cannabis and is responsible for cannabis-… Vehicle control groups received
the control solution used for … ’ when the head of the rat was facing the object within 3 cm of …

… of the brain to stress (Gorzalka et al., 2008) and (iii) third, activation of the CB1 cannabinoid
… The current study demonstrated that the phospho-GSK3β/GSK3β ratio was up-regulated …

… cellular processes regulated by the PI3K/AKT pathway, this … in an experimental model of
brain injury induced by … , while restoring PI3K/AKT/GSK-3β signaling pathway in limbic regions …

… Cannabinoid compounds act through Cannabinoid type 1 … levels to values comparable to
the control group (sham-vehicle… to neurodegeneration and correcting PI3K/Akt/GSK-3β signal …

… -regulated the expression ratio of Bax to Bcl-2. These effects were inhibited by cannabinoid
… these neuroprotective effects are regulated by the CNR1/PI3K/AKT pathway in the brain. …

… The mice that were administered only LPI exhibited no statistically significant differences
in brain weight and tail length compared to the control mice. In addition, there were no tail …

… 9, and caspase-3 & activates the mitochondrial death pathway. PI3K/Akt/GSK-3β pathway
when … PI3K signaling in ischemic stroke holds a special role in the control and regulation of cell …

… animals were perfused and their brains removed and processed, for … Thus, PI3K may control
both seizures and postictal changes, … Therefore, we evaluated the cannabinoid effect in mice …

… The signal transduction pathways regulate diverse biological functions including nutrient …
of ERK reduces or blocks cytotoxicity and thus brain injuries (such as seizures, cerebral …