Effect of Tert-Butyl Hydroperoxide in Testicular Metabolism: A protective role for Regucalcin?

RVL Martins - 2019 - search.proquest.com
… between the somatic Sertoli cells (SCs) and germ cells. SCs … regucalcin (RGN) actions in
intracellular signaling pathways. … the administration of 17βestradiol (E2) in the rat liver lead to …

Regucalcin as one of the Guardians of the Male Reproductive Function

AM dos Santos Silva - 2020 - search.proquest.com
… germ cells in different stages of development and Sertoli cells … can be converted to -dihydrotestosterone
(DHT), which is … actively synthesize estrogens, including 17β-estradiol (E2), …

In vivo and in vitro short-term bisphenol A exposures disrupt testicular energy metabolism and negatively impact spermatogenesis in zebrafish

H Batista-Silva, K Rodrigues, KRS de Moura… - Reproductive …, 2022 - Elsevier
rat Sertoli cells [32] and induce apoptosis of rat and mice germ cells via activation of mitochondrial
apoptotic pathways [… of the testicular cells in the control group by highlighting a normal …

Effects of Glyphosate-Based Herbicides and Glyphosate Exposure on Sex Hormones and the Reproductive System: From Epidemiological Evidence to Mechanistic …

P Tajai, D Pruksakorn, SC Chattipakorn… - Environmental …, 2023 - Elsevier
… studies on their impact on sex hormone regulation and reproductive system. Evidence suggests
… Mechanistically, they interfere with hormone signaling pathways by disrupting proteins …

Caloric restriction alters the hormonal profile and testicular metabolome, resulting in alterations of sperm head morphology

AD Martins, I Jarak, T Morais… - American Journal …, 2020 - journals.physiology.org
… For that, juvenile male Wistar rats (Rattus norvegicus) were … depend on the lactate synthesized
from glucose by Sertoli cells (… target of rapamycin (mTOR) signaling pathway. The protein …

[HTML][HTML] Six decades of research on human fetal gonadal steroids

S Connan-Perrot, T Léger, P Lelandais… - International Journal of …, 2021 - mdpi.com
… endocrine somatic cells differentiate: Sertoli cells from the … 17β-estradiol (E2), can be achieved
through several complex … and detect multiple steroid signaling pathways. The unexpected …

[PDF][PDF] Loredana Assisi1, Alessandra Pelagalli2, 3, Caterina Squillacioti4*, Giovanna Liguori4, Chiara Annunziata5 and Nicola Mirabella4

O Gualillo, M López, CE Perez-Leighton, C Squillacioti… - academia.edu
… to investigate OxA-mediated modulation of 17β-estradiol (17β-E) … within Sertoli cells in
immature animals and in Leydig and germ … Leydig cells oxidation damage and apoptosis through …

Effects and modes of action of exogenous androgens on gonadal steroidogenesis in male mummichog (Fundulus heteroclitus)

R Rutherford - 2020 - scholars.wlu.ca
… the terminal sex hormones testosterone, 17β-estradiol and 11-… Using model androgens
-dihydrotestosterone (DHT) and 17α… in the Leydig and Sertoli cells, which are responsible for …

Synergistic effects of auraptene and 17-β estradiol on traumatic brain injury treatment: oxidant/antioxidant status, inflammatory cytokines and pathology

Z Keshavarzi, S Amiresmaili, M Nazari… - International Journal …, 2023 - Taylor & Francis
… Edema, inflammation and apoptosis in the brain tissue were induced in TBI rats. The number
of apoptotic cells (%) in the E2 (20.41 ± 2.67) treatment group was significantly lower than …

[HTML][HTML] Aflatoxin B1 induces infertility, fetal deformities, and potential therapies

S Francis, NK Kortei, M Sackey, SA Richard - Open Medicine, 2024 - degruyter.com
17β-estradiol is produced by Leydig cells as a result of a feedback reaction to luteinizing
hormone (LH) and by Sertoli cells … of plasma testosterone and -dihydrotestosterone (5α-DHT) …