Contribution of B cells to cortical damage in multiple sclerosis
P Bhargava, HP Hartung, PA Calabresi - Brain, 2022 - academic.oup.com
… most B cells in parenchymal and meningeal infiltrates from … in ageing mice B cells from the
periphery populated the CNS … the meninges, plaques and CSF and some B-cell clones were …
periphery populated the CNS … the meninges, plaques and CSF and some B-cell clones were …
[HTML][HTML] Breaching brain barriers: B cell migration in multiple sclerosis
C Rodriguez-Mogeda, S Rodríguez-Lorenzo, J Attia… - Biomolecules, 2022 - mdpi.com
… brain parenchyma and the subarachnoid spaces of the meninges, … aggregates, and
parenchyma infiltrates, although many clones … This might create an ideal microenvironment for B …
parenchyma infiltrates, although many clones … This might create an ideal microenvironment for B …
[HTML][HTML] B cells in central nervous system disease: diversity, locations and pathophysiology
… This is emphasized in multiple sclerosis, in which B cell-… the meningeal B cell aggregates
suggests that B cells are … CNS parenchyma and either directly damage CNS cells or may …
suggests that B cells are … CNS parenchyma and either directly damage CNS cells or may …
[HTML][HTML] Longitudinally persistent cerebrospinal fluid B cells can resist treatment in multiple sclerosis
… ), meninges, and CNS parenchyma of MS patients. We sought to investigate the presence
of clonally related B cells … of clonal B cell persistence in CSF and blood, even in patients on …
of clonally related B cells … of clonal B cell persistence in CSF and blood, even in patients on …
[HTML][HTML] Selective emergence of antibody-secreting cells in the multiple sclerosis brain
L Bogers, HJ Engelenburg, M Janssen, PPA Unger… - …, 2023 - thelancet.com
… -homing B cells have been identified in multiple sclerosis (MS), … , we freshly obtained
post-mortem blood, CSF, meninges and … T cells invade the brain parenchyma in multiple sclerosis …
post-mortem blood, CSF, meninges and … T cells invade the brain parenchyma in multiple sclerosis …
[HTML][HTML] … between B cells, microglia and macrophages, and implications to central nervous system compartmentalized inflammation and progressive multiple sclerosis
… B cells can be enriched within meningeal immune-cell aggregates of multiple sclerosis (MS)
patients… IL-10 expressing B cells induce myeloid cell molecules associated with quiescence …
patients… IL-10 expressing B cells induce myeloid cell molecules associated with quiescence …
Intrathecal B cells in multiple sclerosis
J Polak - 2024 - duo.uio.no
… can be found in the CSF, meninges, parenchyma, and … in the meninges, where T and B
cells, FDCs, and PBs create compact … We investigate whether the most expanded B-cell clones …
cells, FDCs, and PBs create compact … We investigate whether the most expanded B-cell clones …
Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders
… -experienced B cells that populate the meninges in aging … Although no B cells were found
in the brain parenchyma (fig. … that dural B cells had no clonal overlap with circulating B cells in …
in the brain parenchyma (fig. … that dural B cells had no clonal overlap with circulating B cells in …
[HTML][HTML] Accumulation of meningeal lymphocytes correlates with white matter lesion activity in progressive multiple sclerosis
SM Ahmed, NL Fransen, H Touil, I Michailidou… - JCI insight, 2022 - ncbi.nlm.nih.gov
… In summary, while the density of meningeal T and B lymphocytes was not associated with …
(meningeal, parenchymal WM, and cerebrospinal fluid) demonstrated shared B cell clones …
(meningeal, parenchymal WM, and cerebrospinal fluid) demonstrated shared B cell clones …
Single-cell profiling of CNS border compartment leukocytes reveals that B cells and their progenitors reside in non-diseased meninges
… cells) and Ighm (two cells) showed high clonal … -parenchymal lesions 38 . Several studies
have also described the presence of meningeal ectopic lymphoid tissue in multiple sclerosis …
have also described the presence of meningeal ectopic lymphoid tissue in multiple sclerosis …