[HTML][HTML] Structural zinc binding sites shaped for greater works: Structure-function relations in classical zinc finger, hook and clasp domains
M Padjasek, A Kocyła, K Kluska, O Kerber… - Journal of Inorganic …, 2020 - Elsevier
… the relationship between structure-function-stability of zinc structural … Relationship between
the architecture of zinc coordination and zinc binding affinity in proteins--insights into zinc …
the architecture of zinc coordination and zinc binding affinity in proteins--insights into zinc …
Architecture and Design of Zinc Protein-Ligand Complexes
DW Christianson, AMK Christianson - Chemical and structural …, 2020 - taylorfrancis.com
… coordination stereochemistry of zinc ligand interactions precedes the discussion of several
tight-binding protein-… of those contributing to zinc protein ligand affinity (other factors might …
tight-binding protein-… of those contributing to zinc protein ligand affinity (other factors might …
Structural basis for zinc-induced activation of a zinc uptake transcriptional regulator
F Liu, Z Su, P Chen, X Tian, L Wu, DJ Tang… - Nucleic Acids …, 2021 - academic.oup.com
… architecture and frequently utilize two or more metal binding … , Fur family proteins possess
two or three metal binding sites. … with four conserved cysteines for zinc coordination; site 2 is …
two or three metal binding sites. … with four conserved cysteines for zinc coordination; site 2 is …
Galvanization of protein–protein interactions in a dynamic zinc interactome
… the role of Zn 2+ in the formation of interprotein sites, their architecture, function, … Zn 2+ ,
which depends on metal-to-protein affinity and composition of the first and second coordination …
which depends on metal-to-protein affinity and composition of the first and second coordination …
Design of a flexible, Zn-selective protein scaffold that displays anti-Irving–Williams behavior
… 2 assembly and adopting a V-shaped architecture (θ int = 102; … the binding affinity of Cu II
ions to the coordination geometries … formation of an unusual tri-Zn coordination motif, which, to …
ions to the coordination geometries … formation of an unusual tri-Zn coordination motif, which, to …
Differentiated Zn (II) binding affinities in animal, plant, and bacterial metallothioneins define their zinc buffering capacity at physiological pZn
K Mosna, K Jurczak, A Krężel - Metallomics, 2023 - academic.oup.com
… composition, protein architecture, or mechanism of zinc site … zinc sites are the most stable,
and high Zn(II) binding affinity … and 2 (TvMT) Zn(II) ions bind in such a way as to coordinate the …
and high Zn(II) binding affinity … and 2 (TvMT) Zn(II) ions bind in such a way as to coordinate the …
Relations between Structure and Zn (II) Binding Affinity Shed Light on the Mechanisms of Rad50 Hook Domain Functioning and Its Phosphorylation
JB Tran, M Padjasek, A Krężel - International Journal of Molecular …, 2022 - mdpi.com
… Zn(II)-binding sites is based on the architecture of the site: the number and the type of
coordinating residuals and number of coordinating … Rad50 such as Zn(II)-to-protein affinity (called …
coordinating residuals and number of coordinating … Rad50 such as Zn(II)-to-protein affinity (called …
Mechanism of zinc transport through the zinc transporter yiiP
… coordination with the Zn 2+ ion and shift away from the Zn 2+ … A major role that Zn 2+ plays
is to stabilize the protein, as … -shaped void architecture. In addition to the IF and OF states, the …
is to stabilize the protein, as … -shaped void architecture. In addition to the IF and OF states, the …
Inside-out design of zinc-binding proteins with non-native backbones
… Ligand SEWING, partially coordinated zinc-binding sites were … affinity for zinc and there is
a very close match between our … architecture is likely to be important for designing zinc-based …
a very close match between our … architecture is likely to be important for designing zinc-based …
An atomistic view of the YiiP structural changes upon zinc (II) binding
… structures featured an architecture shared among all CDF … one channel out of the two protein
chains in the dimer. Our … we could observe the coordination sphere of the zinc(II) ion in the …
chains in the dimer. Our … we could observe the coordination sphere of the zinc(II) ion in the …