Three-in-one functional silica nanocarrier with singlet oxygen generation, storage/release, and self-monitoring for enhanced fractional photodynamic therapy

L Jiao, X Zhang, J Cui, X Peng… - ACS applied materials & …, 2019 - ACS Publications
… , 2-pyridone, and Cy7) were not modified on the surface but doped inside the FSNC based
… the 1 O 2 released by endoperoxide under dark (see Scheme 1; 1 O 2 storage/release unit). …

Epidermal growth factor receptor-targeted delivery of a singlet-oxygen sensitizer with thermal controlled release for efficient anticancer therapy

J Chen, D Li, B Huo, F Zhang, X Zhao… - Molecular …, 2019 - ACS Publications
… Photodynamic therapy (PDT) utilizing light-induced singlet oxygen has achieved attractive
… drug erlotinib into the singlet-oxygen chemical source endoperoxide to achieve an EGFR-…

[HTML][HTML] De novo design of polymeric carrier to photothermally release singlet oxygen for hypoxic tumor treatment

T Huang, M Zhao, Q Yu, Z Feng, M Xie, S Liu… - Research, 2019 - spj.science.org
Endoperoxides allow thermally releasing singlet oxygen ( 1 … Structural modification at the
C2-position of the naphthalene … B1 could provide enough heat to trigger 1 O 2 release and P1-…

Recent near-infrared light-activated nanomedicine toward precision cancer therapy

X Luan, Y Pan, Y Gao, Y Song - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
… , while the latter yields cytotoxic singlet oxygen ( 1 O 2 ) … in endoperoxides of 2-pyridone,
which in turn could release 1 … inorganic PTAs with the surface plasmon resonance (SPR) …

Photochromic materials as a photosensitizer in reversible reactive singlet oxygen generation

LK Gulati, GK Gulati, S Kumar - Dyes and Pigments, 2022 - Elsevier
… desirable feature of regulated generation of singlet oxygen [104]. Moreover, the use … singlet
oxygen (in the form of endoperoxides), which can be photolytically or thermolytically released

Photodecaging of a mitochondria-localized iridium (III) endoperoxide complex for two-photon photoactivated therapy under hypoxia

S Kuang, F Wei, J Karges, L Ke, K Xiong… - Journal of the …, 2022 - ACS Publications
singlet oxygen ( 1 O 2 ). To overcome this limitation, we report on a novel mitochondria-localized
iridium(III) endoperoxide … or heat exposure (Scheme 1A), EPOs are able to release the …

Capture and release of singlet oxygen in coordination-driven self-assembled organoplatinum (II) metallacycles

YQ He, W Fudickar, JH Tang, H Wang… - Journal of the …, 2020 - ACS Publications
heating of the neat endoperoxide under inert atmosphere at 120 C for 4 h, the resulting
endoperoxide … to react with singlet oxygen to form the corresponding endoperoxides (EPOs), …

The synthesis and anti-cancer efficacy of endoperoxide modified copper sulfide-ferritin nanocages as PDT and PTT agents

M Kucukoflaz, S Ulusoy, B Korkmaz, SC Ozturk… - Journal of Nanoparticle …, 2023 - Springer
… functionalization comes from the consideration of the bio-compatible, non-toxic, and heat-…
for both PTT and for heating endoperoxides for singlet oxygen production for PDT. For this …

Chemically triggered release of singlet oxygen from bisphenalenyl endoperoxides with a brønsted acid

M Imran, MS Chen - Organic Letters, 2022 - ACS Publications
heat to trigger O 2 release. Here we present the first example of acid-… singlet oxygen ( 1
O 2 ) release that does not require external heating by treating bisphenalenyl endoperoxides (…

Protein-activatable diarylethene monomer as a smart trigger of noninvasive control over reversible generation of singlet oxygen: a facile, switchable, theranostic …

HB Cheng, B Qiao, H Li, J Cao, Y Luo… - Journal of the …, 2021 - ACS Publications
The development of activatable photosensitizers to allow for the reversible control of singlet
oxygen ( 1 O 2 ) production for photodynamic therapy (PDT) faces great challenges. …