[HTML][HTML] VCE-005.1, an hypoxia mimetic betulinic acid derivative, induces angiogenesis and shows efficacy in a murine model of traumatic brain injury
ME Prados, C Navarrete, A García-Martín… - Biomedicine & …, 2023 - Elsevier
… , increased neovascularization and preserved BBB integrity … mice showed significant
improvement in motor coordination … additional clinical tests for cognitive function and memory …
improvement in motor coordination … additional clinical tests for cognitive function and memory …
[HTML][HTML] Angiotensin-(1-7) improves cognitive function and reduces inflammation in mice following mild traumatic brain injury
RP Bruhns, MI Sulaiman, M Gaub, EH Bae… - Frontiers in Behavioral …, 2022 - frontiersin.org
… cognitive impairment following closed TBI. This study examined the therapeutic effect of
Ang-(1-7) on secondary injury observed in a murine model … for cognition and motor coordination …
Ang-(1-7) on secondary injury observed in a murine model … for cognition and motor coordination …
The role of BDNF in experimental and clinical traumatic brain injury
D Gustafsson, A Klang, S Thams… - International journal of …, 2021 - mdpi.com
… Traumatic brain injury is one of the leading causes of mortality … animal models assessing
BDNF expression following injury as … Both found preserved preserved cognitive function in met-…
BDNF expression following injury as … Both found preserved preserved cognitive function in met-…
Resolvin D1 ameliorates cognitive impairment following traumatic brain injury via protecting astrocytic mitochondria
YZ Ren, BZ Zhang, XJ Zhao… - Journal of …, 2020 - Wiley Online Library
… + vehicle group (Figure S1a and b). Taken together, these results indicate that motor coordination
… of an SPM, RvD1, on cognitive impairments in an animal model of TBI, focusing on the …
… of an SPM, RvD1, on cognitive impairments in an animal model of TBI, focusing on the …
[HTML][HTML] Neuroprotective effect of remote ischemic preconditioning in patients undergoing cardiac surgery: A randomized controlled trial
S Zhu, Z Zheng, W Lv, P Ouyang, J Han… - Frontiers in …, 2022 - frontiersin.org
… animal models of cerebral ischemia, it was reported that RIPC enhanced the recovery of
cortical neuronal activity, preserved cerebral … in cognitive function in the sham control group. In …
cortical neuronal activity, preserved cerebral … in cognitive function in the sham control group. In …
[HTML][HTML] Xenon improves long-term cognitive function, reduces neuronal loss and chronic neuroinflammation, and improves survival after traumatic brain injury in mice
R Campos-Pires, T Hirnet, F Valeo, BE Ong… - British journal of …, 2019 - Elsevier
… an animal model that administration of xenon after TBI improves short-term (up to 4 days) and
long-term outcomes (28 days) in mice. … Overall, xenon treatment preserved neuronal white …
long-term outcomes (28 days) in mice. … Overall, xenon treatment preserved neuronal white …
Neuro-inflammation modulation and post-traumatic brain injury lesions: from bench to bed-side
… and preserves post-TBI cognitive function in mice [143]. … walking, thus a better motor
coordination and a better memory [169]… therapeutic drugs tested in both animal models of TBI and …
coordination and a better memory [169]… therapeutic drugs tested in both animal models of TBI and …
Traumatic brain injury: mechanistic insight on pathophysiology and potential therapeutic targets
… traumatic encephalopathy caused by head trauma (Safinia et al. 2016). TBI treatment, which
may involve pharmacotherapy, cognitive … It has been extensively reported in animal models …
may involve pharmacotherapy, cognitive … It has been extensively reported in animal models …
The role of acid sphingomyelinase inhibition in repetitive mild traumatic brain injury
GM Niziolek, RS Hoehn, AP Seitz, PL Jernigan… - Journal of Surgical …, 2021 - Elsevier
… inhibition would preserve neuronal regeneration and decrease … murine model of repetitive
mild traumatic brain injury (rmTBI). Our … inflammation, cognitive and motor impairment, and a …
mild traumatic brain injury (rmTBI). Our … inflammation, cognitive and motor impairment, and a …
Revisiting traumatic brain injury: from molecular mechanisms to therapeutic interventions
… Further, U83836E also showed the ability to preserve … the cerebral damage, and improved
cognition and motor ability [… resolution in a murine model of intracerebral hemorrhage (ICH) …
cognition and motor ability [… resolution in a murine model of intracerebral hemorrhage (ICH) …