Renin angiotensin system blockage by losartan neutralize hypercholesterolemia-induced inflammatory and oxidative injuries

AMS AlSaad, F Alasmari, HM Abuohashish… - Redox …, 2020 - Taylor & Francis
… of antioxidant enzymes were prominently improved in LT … and kidney tissues were
ameliorated by LT. Conclusion: This study confirmed the pathological enrollment of reninangiotensin

The reninangiotensin system in cardiovascular autonomic control: recent developments and clinical implications

AJ Miller, AC Arnold - Clinical Autonomic Research, 2019 - Springer
… Cardiovascular disease remains the leading cause of … to suppress efferent sympathetic
outflow reduces circulating … diabetes or moderate to severe renal impairment. In hypertensive rats…

Effect of mineralocorticoid receptor antagonism and ACE Inhibition on angiotensin profiles in diabetic kidney disease: An exploratory study

JJ Kovarik, CC Kaltenecker, O Domenig, M Antlanger… - Diabetes Therapy, 2021 - Springer
Renin While ACE Activity Remains Suppressed Both renin and aldosterone concentrations
were prominently … diabetes-induced hypertension and renal damage in human studies. While …

[HTML][HTML] Potential effects and application prospect of angiotensin receptor-neprilysin inhibitor in diabetic kidney disease

X Zhang, Y Zhou, R Ma - Journal of Diabetes and its Complications, 2022 - Elsevier
… , suggesting a reduction of renal injury characterized by necrosis … ARNI may have effects
of ameliorating renal dysfunction. … resistance by activation of renin-angiotensin system, which …

… of the novel nonsteroidal mineralocorticoid receptor blocker, esaxerenone (CS-3150), on blood pressure and urinary angiotensinogen in low-renin Dahl salt-sensitive …

L Li, Y Guan, H Kobori, A Morishita, H Kobara… - Hypertension …, 2019 - nature.com
… for renal injury and cardiovascular disease [1, 9], it is important to … suppressed reninangiotensin
system (RAS) due to reduced … that both losartan and esaxerenone suppressed the renal

[HTML][HTML] … angiotensin converting enzyme inhibitor and angiotensin receptor antagonist on systemic and tissue levels in rats with experimentally-induced chronic renal …

AO Sehirli, S Sayiner, A Velioğlu-Oğünç… - Pak. J …, 2020 - researcherslinks.com
… an important factor in the pathogenesis of chronic renal failure … was suppressed through
the blocking of angiotensin AT1 … that act by blocking the renin-angiotensin system. This study …

Galangin attenuates oxidative stress-mediated apoptosis in high glucose-induced renal tubular epithelial cells through modulating reninangiotensin system and PI3K …

J Liao, B Liu, K Chen, S Hu, ZY Liu, YX Li… - Toxicology …, 2021 - academic.oup.com
… ) inhibitor [12], and alleviate the renal damage induced by … suppress oxidative stress injury
of renal cells induced by HG … most important in HG-induced oxidative stress injury of renal cells…

2020 update on the reninangiotensin–aldosterone system in pediatric kidney disease and its interactions with coronavirus

AC Simoes e Silva, K Lanza, VA Palmeira, LB Costa… - Pediatric …, 2021 - Springer
… a two-arm, counter-regulatory system, with the most important peptides being Ang II and …
renin. The formation of Ang II by means of the removal of two amino acids from angiotensin I (…

Coronavirus disease 2019 and hypertension: the role of angiotensin-converting enzyme 2 and the renin-angiotensin system

DL Edmonston, AM South, MA Sparks… - … in chronic kidney disease, 2020 - Elsevier
… may also both hold the key to SARS-CoV-2 entry into … However, this association has
multiple caveats, most important of … suppression of ACE2/Ang-(1-7) likely propagate lung injury

α2A-Adrenoceptors modulate renal sympathetic neurotransmission and protect against hypertensive kidney disease

L Hering, M Rahman, H Hoch, L Markó… - Journal of the …, 2020 - journals.lww.com
renin-angiotensin system, such as hypertensive kidney … and hypertensive kidney disease,
we induced angiotensin II (AngII)… and NKCC2 was significantly suppressed in both α2A-AR-KO …