Natural products against renin-angiotensin system for antifibrosis therapy
T Yang, YY Chen, JR Liu, H Zhao, ND Vaziri… - European journal of …, 2019 - Elsevier
… studies suggest that both RAS axes may play an important role in the … PZG and PZH
suppressed the TGF-β/Smad pathway by … via ameliorating multiple mitochondrial dysfunctions …
suppressed the TGF-β/Smad pathway by … via ameliorating multiple mitochondrial dysfunctions …
The renin-angiotensin system modulates endotoxic postconditioning of exacerbated renal vasoconstriction in preeclamptic offspring
HA Morgaan, MY Sallam, HM El-Gowelli… - Scientific Reports, 2023 - nature.com
… Ang1-7 supplementation ameliorates the PE-related … the present study revealed two important
findings that establish a … preconditioning of renal injury via suppressing the transcription of …
findings that establish a … preconditioning of renal injury via suppressing the transcription of …
Inhibition of the renin-angiotensin system in the cardiorenal syndrome with anaemia: a double-edged sword
… association of heart failure and renal impairment and to hint at … These changes were
ameliorated by pretreatment with an ARB … of uremic toxins and bone marrow suppression, as well …
ameliorated by pretreatment with an ARB … of uremic toxins and bone marrow suppression, as well …
Selective inhibition of the C-domain of ACE (angiotensin-converting enzyme) combined with inhibition of NEP (Neprilysin): a potential new therapy for hypertension
R Alves-Lopes, AC Montezano, KB Neves, A Harvey… - …, 2021 - Am Heart Assoc
… The renin-angiotensin-aldosterone system plays an important … , ACE inhibitor drugs that are
used clinically target both C- … S5A), an effect that was ameliorated by treatment with lisW-S, …
used clinically target both C- … S5A), an effect that was ameliorated by treatment with lisW-S, …
[HTML][HTML] Overexpression of microRNA-21 mediates Ang II-induced renal fibrosis by activating the TGF-β1/Smad3 pathway via suppressing PPARα
H Lyu, X Li, Q Wu, L Hao - Journal of Pharmacological Sciences, 2019 - Elsevier
… treated mice effectively ameliorated the abnormally activated … to be harmful for renal fibrosis.2,
3 Angiotensin II (Ang II), the … patients still develop kidney fibrosis and renal failure due to …
3 Angiotensin II (Ang II), the … patients still develop kidney fibrosis and renal failure due to …
An update on the tissue renin angiotensin system and its role in physiology and pathology
… ACE2 in the suppression of Ang-II-mediated heart failure. In … has been shown to ameliorate
liver fibrosis through reduction of … enhanced renal damage in models of renal insufficiency by …
liver fibrosis through reduction of … enhanced renal damage in models of renal insufficiency by …
Sacubitril/valsartan treatment has differential effects in modulating diabetic kidney disease in db/db mice and KKAy mice compared with valsartan treatment
… renin-angiotensin blockade has shown beneficial outcomes in patients with diabetes, renal
injury … models, and pharmacological inhibition of STING ameliorated kidney fibrosis in mouse …
injury … models, and pharmacological inhibition of STING ameliorated kidney fibrosis in mouse …
Effects of exercise training on renal interstitial fibrosis and renin–angiotensin system in rats with chronic renal failure
S Yamakoshi, T Nakamura, N Mori, C Suda… - Journal of …, 2021 - journals.lww.com
… training might ameliorate the imbalance of renal RAS and inhibit renal interstitial fibrosis by
… performed by removal of the left and two-thirds infarction of the right kidney under anesthesia …
… performed by removal of the left and two-thirds infarction of the right kidney under anesthesia …
Knockdown of periostin attenuates 5/6 nephrectomy‐induced intrarenal renin–angiotensin system activation, fibrosis, and inflammation in rats
X Bian, Y Bai, X Su, G Zhao, G Sun… - Journal of cellular …, 2019 - Wiley Online Library
… , two important chemotactic factors, than untransfected cells. Conditioned medium from HK-2
… We further found that inhibition of periostin improved renal function, suppressed intrarenal …
… We further found that inhibition of periostin improved renal function, suppressed intrarenal …
The interaction partners of (pro) renin receptor in the distal nephron
… The renin-angiotensin system (RAS) has been known for … , accompanied with ameliorated
renal injury and the lower … 32-suppressed PRR/sPRR and prorenin/renin expression and …
renal injury and the lower … 32-suppressed PRR/sPRR and prorenin/renin expression and …