G protein-coupled receptor signaling in VTA dopaminergic neurons bidirectionally regulates the acute locomotor response to amphetamine but does not affect …

AH Runegaard, D Dencker, G Wörtwein, U Gether - Neuropharmacology, 2019 - Elsevier
… (DREADDs) that the acute hyperlocomotor response to AMPH is … -positive, dopaminergic
ventral tegmental area (VTA) neurons … of rM3Ds could by itself promote a sensitized response to …

Lack of dopamine D4 receptor participation in mouse hyperdopaminergic locomotor response

IM Liao, JC Chen - Behavioural Brain Research, 2021 - Elsevier
… ’s reward center, the ventral tegmental area (VTA), while the … avoidance response and
PCP-induced hyperlocomotion, in … of METH-sensitized mice requires further experimentation. …

Reelin deficiency exacerbates cocaine‐induced hyperlocomotion by enhancing neuronal activity in the dorsomedial striatum

G de Guglielmo, A Iemolo, A Nur… - Genes, Brain and …, 2022 - Wiley Online Library
responses to cocaine lead to increased dopamine levels in the ventral tegmental area and
… not account for the possible sensitizing effects of repeated cocaine administration. However, …

[HTML][HTML] Role of the orexinergic system within the ventral tegmental area in the development of sensitization to morphine induced by lateral hypothalamus stimulation

A Haghparast, M Rashvand - Basic and Clinical Neuroscience, 2022 - ncbi.nlm.nih.gov
… of LH induces sensitization to the antinociceptive response … In this respect, certain similar
studies indicated that repeated … and the prefrontal cortex in morphine sensitized rats. However, …

Role of orexinergic receptors within the ventral tegmental area in the development of morphine sensitization induced by forced swim stress in the rat

S Mazaheri, M Zendehdel, A Haghparast - Progress in Neuro …, 2022 - Elsevier
Repeated exposure to stress enhances sensitivity to drugs … sensor, and a thermal stimulus
was applied in succession 3, 5… study, the antinociceptive response was elicited five min …

Individual differences in amphetamine locomotor sensitization are accompanied with changes in dopamine release and firing pattern in the dorsolateral striatum of …

RI Gatica, MÍ Aguilar-Rivera, VH Azocar, JA Fuentealba - Neuroscience, 2020 - Elsevier
areas of the motivation circuit, such as the ventral tegmental … To define if a rat sensitized or
not to repeated AMPH … -test), showing that the induced hyperlocomotion on day 5 and 11 is in …

Profiling of behavioral effects evoked by ketamine and the role of 5HT2 and D2 receptors in ketamine-induced locomotor sensitization in mice

JP Galvanho, AC Manhaes… - Progress in Neuro …, 2020 - Elsevier
… both escalated in response to repeated ketamine exposure … that innervate the ventral tegmental
area and nucleus accumbens … play a role on ketamine hyperlocomotor effects as well as …

mGlu5 in GABAergic neurons modulates spontaneous and psychostimulant-induced locomotor activity

CS Wu, CP Jew, H Sun, CJ Ballester Rosado… - …, 2020 - Springer
… mGlu5 in dopaminergic neurons in the ventral tegmental area (VTA). … of hyperlocomotion
response to cocaine, and delayed the … Future studies employing drug-seeking, sensitizing, and …

Roles of nucleus accumbens shell and core in footshock-induced stress altering behavioral sensitization by methamphetamine in acquisition and testing: Running …

CN Cheng, ACW Huang, SJ Wu - Behavioural Brain Research, 2020 - Elsevier
… adaptations in response to repeated exposure to … In particular, the pathway of the ventral
tegmental area (VTA) … prefrontal cortex, and chronic stress sensitized the reward circuit from the …

Win-paired cues modulate the effect of dopamine neuron sensitization on decision making and cocaine self-administration: divergent effects across sex

TJ Hynes, CS Chernoff, KM Hrelja, TL Maric… - Biological …, 2024 - Elsevier
… interactions, we sensitized ventral tegmental area DA neurons … chemogenetic methods
sensitized the locomotor response to … We showed that a regimen of repeated, daily stimulation of …