… The Wnt/β-catenin signaling pathway is named after its … The likely candidates for the repressive
signals are ectodermal … Taken together, during the early stages of skeletogenesis in the …

… and enhanced Wnt/β-catenin signaling in osteocytes [89]. … of β-catenin and suppression of
Wnt/β-catenin signaling were … a higher incidence of cardiovascular events has been raised […

… These events start the expression of PPARγ C/EBPα, both … to differentiate into adipocytes,
osteocytes, or chondrocytes. … It seems that the main role of suppression is to increase the MSC …

… The same sequence of events is presumed to take place … osteocyte number, shape, or size.
Sclerostin deficiency is thought to lead to an increase in endogenous Wnt/β-catenin signaling …

… use of zoledronate as no improvement in event-free survival was … EMT is characterized by
repression of key components of the … Indeed, osteoblasts and their precursors, osteocytes and …

… that osteocytes initiate the cascade of events that lead to … of canonical Wnt/β-catenin
signaling in osteocytes (daβcat Ot … , instead of osteocytes, is responsible for the suppression of …

… a series of events that prevent β-catenin degradation, which … , Wnt-β catenin pathway
activity in osteoblasts and osteocytes … repress the expression of E-cadherin [101]. In addition, β-…

… in osteocytes; moreover, canonical Wnt/β-catenin pathway was … The suppression of osteoblast
activity, and the enhanced activity … , deeply involved in the intracellular events leading to …

… stimulation of Wnt/β-catenin signaling in osteocytes results in … by osteocytes in adult bone,
prevents skeletal-related events … antagonists, osteocytes also contribute to the suppression of …

… The inhibition of Wnt/β-catenin signaling shifted MSC lineage commitment to adipocyte
and … by osteocytes through paracrine activity and relieves the repression of Wnt signaling to …