Large-scale genome mining allows identification of neutral polymorphisms and novel resistance mutations in genes involved in Candida albicans resistance to …

…, AT Coste, T Obadia, C Maufrais… - Journal of …, 2020 - academic.oup.com
Point mutations in genes involved in resistance to … chromosome aneuploidies leading to
copy number variations of … albicans isolates are compared with the genome (haplotype A) of …

Loss of heterozygosity: its impact on generating and shaping genetic variations in human fungal pathogen candida albicans

TB Marton - 2020 - theses.hal.science
Candida albicans is an opportunistic human pathogen possessing a relatively heterozygous
diploid genome that is highly tolerant to particular genomic rearrangements, namely loss-of-…

Identification of recessive lethal alleles in the diploid genome of a Candida albicans laboratory strain unveils a potential role of repetitive sequences in buffering their …

T Marton, A Feri, PH Commere, C Maufrais, C d'Enfert… - MSphere, 2019 - Am Soc Microbiol
… Complementation with a wild-type copy of MTR4 rescued … a LOH event, even though point
mutations in the URA3 gene … one haplotype of Chr7 was used for haplotype characterization …

Population genomics of the pathogenic yeast Candida tropicalis identifies hybrid isolates in environmental samples

CE O'Brien, J Oliveira-Pacheco, E Ó Cinnéide… - PLoS …, 2021 - journals.plos.org
… , a hybrid of Saccharomyces cerevisiae and Saccharomyces … Smaller copy number variants
(CNVs) were identified in several … compared it with both haplotype A and haplotypes B and C

Genomic evidence for a hybrid origin of the yeast opportunistic pathogen Candida albicans

V Mixão, T Gabaldón - BMC biology, 2020 - Springer
… put these alternative hypotheses at test by comparing C. … Similar results were obtained for
the two haplotypes, and … a chromosomal set composed of a copy from each parent for all the …

Strain background of Candida albicans interacts with SIR2 to alter phenotypic switching

AL Woodruff, J Berman, M Anderson - Microbiology, 2024 - microbiologyresearch.org
… (LOH), copy number variations (CNVs) and point mutations that can … elegans or Saccharomyces
cerevisiae found different … Δ/Δ mutants is a trisomic Chr6 with an ABB haplotype. High-…

Antifungal susceptibility of clinical yeast isolates from a large Canadian reference laboratory and application of whole-genome sequence analysis to elucidate …

LR McTaggart, A Cabrera, K Cronin… - Antimicrobial Agents …, 2020 - Am Soc Microbiol
Comparison of genome-wide copy number variation between … albicans (55), and point
mutations and increased expression of … albicans SC5314 haplotype A version A22, C. glabrata …

Partner Choice in Spontaneous Mitotic Recombination in Wild Type and Homologous Recombination Mutants of Candida albicans

A Bellido, T Ciudad, B Hermosa… - G3: Genes …, 2019 - academic.oup.com
… (A) Approach used in this work to generate tester strains with … homologs exhibit size differences
sufficient for separation on … -out of URA3 and one copy of the two hisG repeats, which can …

Population Analysis and Evolution of Saccharomyces cerevisiae Mitogenomes

D Vieira, S Esteves, C Santiago, E Conde-Sousa… - Microorganisms, 2020 - mdpi.com
… sequences, and point mutations have culminated in a high … polymorphic sites and 38.63
pairwise differences, in average, … faster disruption of newly formed haplotypes, as also detected …

Identification of Essential Genes and Fluconazole Susceptibility Genes in Candida glabrata by Profiling Hermes Transposon Insertions

AN Gale, RM Sakhawala, A Levitan… - G3: Genes …, 2020 - academic.oup.com
… bakers’ yeast Saccharomyces cerevisiae than to C. … of Hermes insertion mutants and the
profiling methods described … , we observed a significant difference between C. glabrata and …