Efficacy of adalimumab as second-line therapy in a pediatric cohort of Crohn's disease patients who failed infliximab therapy: the Italian Society of Pediatric …

P Alvisi, S Arrigo, S Cucchiara, P Lionetti… - … : Targets and Therapy, 2019 - Taylor & Francis
… We performed a retrospective, multicenter, cohort analysis of 44 CD pediatric patients
with moderate–severe CD activity who had been treated with Ifx and were switched to Ada …

Efficacy and safety of adalimumab in pediatric patients with Crohn's disease: A systematic review and meta-analysis

B Chen, Z Zou, X Zhang, D Xiao, X Li - European Journal of Clinical …, 2024 - Springer
… (5) Study design: randomized controlled trials (RCTs) and retrospective or prospective
cohort studies assessing predefined outcomes; case–control studies and conference abstract …

Adalimumab Biosimilar in Pediatric Inflammatory Bowel Disease: A Retrospective Study from the Sicilian Network for Inflammatory Bowel Disease (SN-IBD)

V Dipasquale, S Pellegrino, M Ventimiglia, M Citrano… - Healthcare, 2024 - mdpi.com
… However, pediatric data are limited. This study aimed to assess the … and safety of adalimumab
biosimilar (ADL-BioS) in pediatric IBD patients. Methods: All consecutive pediatric IBD …

Adalimumab in Pediatric Inflammatory Bowel Disease

SY Choi, B Kang - Frontiers in Pediatrics, 2022 - frontiersin.org
… In a 2018 retrospective study in Spain, ADL treatment results … personalized anti TNF therapy
in CD study (PANTS) of children … However, this study was conducted retrospectively, and the …

[PDF][PDF] Long-term efficacy of anti-tumor necrosis factor agents in pediatric luminal Crohn's disease: A systematic review of real-world evidence studies

H Van Rheenen… - Pediatric Gastroenterology …, 2020 - synapse.koreamed.org
anti-TNF therapy 1, 2, and 3 years after initiation. Results: In total, 2,464 papers were screened,
94 were selected for full text review… two of these to be retrospective cohort studies [19,20]. …

… therapy of adalimumab with an immunomodulator is not more effective than adalimumab monotherapy in children with Crohn's disease: a post hoc analysis of the …

M Matar, R Shamir, D Turner, E Broide… - Inflammatory Bowel …, 2020 - academic.oup.com
… ” to anti-TNF therapy (including … pediatric studies: Although 1 previous retrospective study
demonstrated a higher remission rate with ADL combination therapy, 18 another retrospective

Adalimumab therapy in pediatric Crohn disease: A 2-year follow-up comparing “top-down” and “step-up” strategies

E Payen, A Neuraz, L Zenzeri, C Talbotec… - Journal of Pediatric …, 2023 - journals.lww.com
… because 95% of the patients in the RESEAT registry had previously received infliximab, and
retrospective study of 62 pediatric patients treated with ADA as first-line anti-TNFα therapy

Biological therapy in pediatric age

F Penagini, L Cococcioni, E Pozzi, D Dilillo… - Pharmacological …, 2020 - Elsevier
… the therapeutic approach and disease course of pediatric inflammatory bowel disease (IBD).
In particular, drugs such as infliximab (IFX) and adalimumab … a retrospective analysis of data …

Anti-TNF Therapies Other Than Infliximab for the Treatment of Pediatric Inflammatory Bowel Disease

S Gold, L Cohen - Pediatric Inflammatory Bowel Disease, 2023 - Springer
… One of the first studies to demonstrate the efficacy of adalimumab in pediatric CD patients …
was the Retrospective Evaluation of the Safety and Effect of Adalimumab Therapy (RESEAT) …

Comparison of Clinical Outcomes in Pediatric Patients with Ileocolonic Crohn Disease Treated with Infliximab Versus Adalimumab

E Fanous, T Marshanski, N Tal, M Matar… - Journal of Pediatric …, 2023 - journals.lww.com
… In the group that received infliximab, 9 had previously failed on adalimumab therapy due
to … The main finding of our retrospective cohort study of patients with ileocolonic CD treated …