… by excess, yet reversible, fat accumulation in the … insulin action, the fat-induced liver insulin
resistance causes a slight rise in fasting plasma glucose and triggers an increase in insulin …

… is reversible, emphasizing the importance of … roles of specific plasma lipid or fatty acid
species in promoting or preventing CVD and the importance of therapeutically modifying plasma …

… reversible condition, but if untreated leads to type 2 diabetes alongside increasing
cardiovascular risk. The link between obesity … of the lipid remodeling occurring in insulin-sensitive …

… Acromegaly constitutes a unique human in vivo model to study reversible insulin resistance
… of insulin resistance dissociated from obesity. We studied twenty-one patients with newly …

… In conclusion, the lipid- induced insulin resistance or lipotoxicity hypothesis proposes that
in … The observation of rapid reversibility of hepatic but not muscle insulin resistance with …

… to impaired pancreatic beta cell function that results in the development of type 2 diabetes. …
that type 2 diabetes is reversible in patients who undergo bariatric surgery for obesity 11 - 13 …

… While lifestyle interventions such as physical activity have been confirmed to have a
positive effect on insulin sensitivity in skeletal muscle, affecting lipid metabolism (205). …

… -diabetes stage, β-cells compensate for insulin resistance through hypersecretion of insulin.
… hypothesis that was proposed to explain the etiology and reversibility of T2DM [28,192]. This …

… the role of weight gain with excess adiposity and obesity in the … We also consider the
reversibility of IR through the effective … with greater improvements in both IR and lipid profile [119]. …

… reversible. As for NASH, there is still no approved pharmacological treatment for liver fibrosis.
… DAGs have been proposed as bioactive lipids that can induce insulin resistance through …