… In 2008, we reported on the uptake of cancer screening and of various prevention options
(surgery and chemoprevention) in 2677 women with a BRCA mutation from nine countries. …

… noninvasive strategies for risk reduction in mutation carriers. … : surveillance, chemoprevention,
and risk-reducing surgery. … with current recommendations and practice at the time of …

… Two large prospective cohort studies supporting this practice … breast cancer risk reduction
in patients with BRCA1/2 mutations. … chemoprevention with tamoxifen or aromatase inhibitors. …

… -reducing surgery, and/or chemoprevention must take into … and hormonal forms of risk
reduction (Table 1). While … , including lack of data on the screening practices of the carriers as well …

… screened the items and selected those most relevant to this review’s scope. BRCA1/2 mutation
… show that antihormonal chemoprophylaxis use in BRCA mutation carriers remains low …

… their positive test result and 33% had risk-reducing bilateral … surgical intervention as part
of their cancer-risk reduction … risk reduction and that they desired a safe chemoprevention …

… are currently no effective non-invasive preventive methods. In … The NCCN recommends
offering genetic testing to high-risk … The risk reduction related to the use of the oCP in BRCA1\…

… It is preferable to identify a mutation in a healthy women prior to … surgical prevention,
chemoprevention and screening (early … mutation carriers: revisiting the evidence for risk reduction. …

… Methods: We developed a Bayesian network model of a … salpingo-oophorectomy (RRSO),
and chemoprevention [8]. … cancer risk and all cause mortality in BRCA 1 and BRCA 2 mutation …

… screening may be considered for women with BRCA1 and BRCA2 germline mutations not
… diphosphate-ribose) inhibitors may have chemopreventive activity. Consequently, the recent …