Development-dependent changes in the NR2 subtype of the N-methyl-D-aspartate receptor in the suprachiasmatic nucleus of the rat

JM Herrera-Zamora… - Journal of …, 2019 - journals.sagepub.com
… indicate that the NR2B subtype plays an important role in the synchronization to light. In …
Cells were discarded if the input resistance was less than 150 MΩ or the access resistance …

[HTML][HTML] A review on chronic pain in rheumatoid arthritis: a focus on activation of NR2B subunit of N-Methyl-D-Aspartate receptors

CAN Ismail - The Malaysian Journal of Medical Sciences: MJMS, 2020 - ncbi.nlm.nih.gov
… allodynia to pressure, heightened sensitivity to light touch and hyperalgesia to innocuous
cold… NR2B subunit-mediated currents that produced the prolonged currents and elevated entry

Enhanced function of NR2C/2D-containing NMDA receptor in the nucleus accumbens contributes to peripheral nerve injury-induced neuropathic pain and depression …

PB Jing, XH Chen, HJ Lu, YJ Gao, XB Wu - Molecular Pain, 2022 - journals.sagepub.com
inputs to the NAc medium spiny neurons (MSNs) are reduced in inflammatory and neuropathic
pain. The N-methyl-d-aspartate receptors (… via increasing NR2B-mediated currents in both …

[HTML][HTML] Increased nociceptive responses in streptozotocin-induced diabetic rats and the related expression of spinal NR2B subunit of N-methyl-D-aspartate receptors

CAN Ismail, R Suppian, CB Abd Aziz… - Diabetes & …, 2019 - synapse.koreamed.org
… to the augmentation of the response to the sensory inputs [6]. … aimed to understand the role
of NR2B in the early pathogenesis of … inputs, specifically mediated by the NMDA or neurokinin …

[HTML][HTML] Advances and Barriers in Understanding Presynaptic N-Methyl-D-Aspartate Receptors in Spinal Pain Processing

A Dedek, ME Hildebrand - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
… the role of preNMDARs in mediating nociceptive spinal cord … the role of preNMDARs in
nociceptive signaling and shed light … directly permitting Ca 2+ entry to the presynaptic terminal and…

Differential roles of NMDAR subunits 2A and 2B in mediating peripheral and central sensitization contributing to orofacial neuropathic pain

YY Zhang, F Liu, ZH Fang, YL Li, HL Liao… - Brain, behavior, and …, 2022 - Elsevier
… The spinal N-methyl-d-aspartate receptor (NMDAR), … roles of NR2A and NR2B in peripheral
and central sensations. … 23 ± 2 C on a constant 12 h light/dark cycle with unlimited access to …

N-Methyl-d-aspartate receptor signaling-protein kinases crosstalk in cerebral ischemia

A Engin, AB Engin - Protein Kinase-mediated Decisions Between Life and …, 2021 - Springer
… In this context, considering the dual roles of NMDA receptors … , calpain-mediated cleavage
of the NR2B subunit in neurons … NMDA-mediated calcium entry, followed by metabolism of …

Role of N-Methyl-D-Aspartate Receptor in Memory Network

Z Dan-shen, SU Xiao-mei - Acta Neuropharmacologica, 2019 - actanp.hebeinu.edu.cn
… 受体,而 N- 甲基 -D- 天冬氨酸 受体(N-methyl-D-aspartate receptor,… NR2B[16],NR2A 在胚胎
时期几乎无法检测到,但 NR2B 的表达量很高,在 出生后的最初几周,NR2A 表达量的增加而 NR2B

Epigenetic-mediated N-methyl-D-aspartate receptor changes in the brain of isolated reared rats

CM Loureiro, HA Fachim, F Corsi-Zuelli, R Shuhama… - …, 2020 - Taylor & Francis
… The N-methyl-D-aspartate receptor (NMDAR) plays an important role in neurodevelopment
[… important that future studies consider the analyses of NR2a and NR2b subunits separately. …

Acid-sensing ion channel 1a modulates NMDA receptor function through targeting NR1/NR2A/NR2B triheteromeric receptors

CL Ma, H Sun, L Yang, XT Wang, S Gao, XW Chen… - Neuroscience, 2019 - Elsevier
… The over-activation of N-methyl-D-aspartate receptors (NMDARs) is the main … mediated [Ca
2+ ] i overload in neurons, and that ASIC1a plays a modulatory role with regard to Ca 2+ entry