… of the role of vascular endothelial growth factor-A (VEGF-A) and endothelial cells in beta cell
… In addition, the therapeutic potential of modulating VEGF-A levels in beta and beta-like cells …

… of pancreatic cells, particularly β-cell and endothelial cells.… can cause a deleterious effect
on an islet cell function in… and PDGF play a major role in pancreatic β-cells regeneration, the …

… The biological function of VEGF-B has long been poorly understood. Despite its
sequence homology with VEGF-A 21 , its role in angiogenesis is limited to conditions of over-expression …

… Since beta cells produce both VEGF-A and PlGF, we then examined expression of both VEGF-A
and PlGF in beta cells in … Interestingly, we found that VEGF-A levels in beta cells remain …

… the vascular cells and β-cells and its role in glucose homeostasis and diabetes. … cells and
neurons (1–4). This review focuses on the crosstalk of β-cells with vascular cells and their role …

… if beta-cells originating from the dorsal and ventral pancreatic … cell assay to mark dorsal
pancreatic bud derived beta-cells 14 . In this assay, H2B-EBFP mRNA is injected into one cell …

… For example, overexpression of VEGF-A in the developing pancreas leads to a
hypervascularized pancreas and ectopic insulin expression [12]. Consistently, knock-out of the anti-…

… We conclude that defective VEGF-A/VEGFR2 dependent signaling in endothelial cells is
the underlying cause of the observed phenotypes, namely reduced intra-islet capillary density …

… starting one day before VEGF-A induction and continuing for 1 week after VEGF-A normalization
(Fig. 2a). … , NF-kB nuclear factor kappa-light-chain-enhancer of activated B cells, PI3K …

… The aim of the present study was to investigate the role of the PKCβII/HuR/VEGF-A pathway
in the development of DR using the Ins2 Akita mouse animal model, which is characterized …