… characterization of CAF subtypes and their specific role in tumor progression could offer
innovative therapeutic tools for the development of anti-tumor treatments. Notwithstanding, these …

… of the role that CAFs play in conferring therapeutic resistance in different … functions of
CSCs are their role in resistance to multiple anticancer therapies and the repopulation of cancer …

… new hints for cancer treatment. Here we review the role of CAFs in cancer drug resistance, …
have been well studied and their functions are well known, which play a major role in drug …

Fibroblasts play an essential role in organogenesis and the … regulate cancer-associated
inflammation and antitumor immunity, … can confer resistance to immune-based therapies for solid …

… of anti-tumor immunity, and resistance to cancer therapy. … their biologic tumor-promoting
functions and recent advancements in the development of CAF-targeting cancer therapies. …

… cancer-associated fibroblasts, which have been implicated in diverse oncogenic roles including
cancer invasion and metastasis, resistance to … their significance as modulators of cancer …

… on anticancer therapies. CAFs, as one of the dominant cell types in the tumor stroma, and
their role in anticancer treatments have … At the CAF origin is an individual factor that reveals its …

… cancer-associated fibroblasts and targeted therapy for cancer | Signal Transduction and
Targeted Therapy … Signaling pathways in cancer-associated fibroblasts and targeted therapy for …

… roles and clinical relevance of CAFs are discussed and summarized with particular emphasis
on their heterogeneity, prognostic value and therapeutic … promotion of anticancer immunity, …

… , are being investigated for their role in anticancer therapy either alone or in combination. …
fibroblasts are subtypes of normal fibroblasts resistant to CAF conversion or distinct anti-tumor …