The implication of reactive oxygen species and antioxidants in knee osteoarthritis

NB Tudorachi, EE Totu, A Fifere, V Ardeleanu… - Antioxidants, 2021 - mdpi.com
… These factors reveal the importance of maintaining a redox … status by increasing the
production of IL-1 and IL-6, or matrix … is required for clinical and diagnostic validation. Because …

Biomarkers of joint damage in osteoarthritis: current status and future directions

R Kumavat, V Kumar, R Malhotra… - Mediators of …, 2021 - Wiley Online Library
… cartilage oligomeric matrix protein; NF-κB: nuclear factor kappa … of anti-inflammatory and
antioxidant drugs on the cartilage [… that adipokines play an important role in OA progression and …

Oxidant/antioxidant disequilibrium in idiopathic pulmonary fibrosis pathogenesis

P Cameli, A Carleo, L Bergantini, C Landi, A Prasse… - Inflammation, 2020 - Springer
… In this context, this review will provide an overview of the pathogenetic role of oxidative/…
an increased expression of matrix metalloproteinases and other extracellular matrix-degrading …

Relationship between aortic wall oxidative stress/proteolytic enzyme expression and intraluminal thrombus thickness indicates a novel pathomechanism in the …

I Wiernicki, M Parafiniuk, A Kolasa-Wołosiuk… - The FASEB …, 2019 - Wiley Online Library
… –related enzymes and matrix metalloproteinase-9 (MMP-9) … We also studied the antioxidant
activity of superoxide … a key role in the pathogenesis of AAA and suggest that antioxidant

Free radicals, oxidative stress-related diseases and antioxidant supplementation.

GA Engwa, FN Nweke… - … Therapies in Health & …, 2022 - search.ebscohost.com
… cannot be used as diagnostic tools to … matrix metalloproteinases that is involved in the
terminal step of collagen degradation. As such, increased prolidase activity may have a critical role

Genetic susceptibility and protein expression of extracellular matrix turnover-related genes in oral submucous fibrosis

RH Cheng, YP Wang, JYF Chang, YH Pan… - International journal of …, 2020 - mdpi.com
… -related genes might play a role in OSMF pathogenesis. Transforming growth factor-β1 (TGF…
, enzymes, corticosteroid, vasodilator and antioxidants have been used for treatment of …

Oxidative stress in the anterior ocular diseases: diagnostic and treatment

A Dammak, C Pastrana, A Martin-Gil… - Biomedicines, 2023 - mdpi.com
role in matrix remodeling [52,53] and has been related to the … , abnormal expression of
several major antioxidant enzymes … 2 overcomes the antioxidant status and disrupts homeostasis…

Antioxidant and anti-inflammatory diagnostic biomarkers in multiple sclerosis: a machine learning study

L Mezzaroba, ANC Simão, SR Oliveira, T Flauzino… - Molecular …, 2020 - Springer
… is expressed in all cells of the body and is associated with … , we first analyzed their correlation
matrices. These results are … have a relative importance in the MS diagnosis. The lower …

Biomarkers of oxidative stress in metabolic syndrome and associated diseases

R Vona, L Gambardella, C Cittadini… - Oxidative medicine …, 2019 - Wiley Online Library
… MS, (ii) contribute to the diagnosis/evaluation of the disease’s … on the role of OS in the
pathogenesis of MS and the related … Nrf2 is an important antioxidant factor involved in controlling …

Evaluation of enzymatic and non-enzymatic antioxidant status and biomarkers of oxidative stress in saliva of patients with oral squamous cell carcinoma and oral …

K Babiuch, A Bednarczyk, K Gawlik… - Acta Odontologica …, 2019 - Taylor & Francis
… ), localized in the mitochondrial matrix, is the most distinct … after provisional (clinical) diagnosis
of cancer or leukoplakia … all salivary antioxidants and is of great clinical significance since …