… Diagnosis of RPL includes the spontaneous demise of a … homeostatic balance between
oxidant and antioxidant state. … antioxidants are the first line of defense and include matrix …

… factor that regulates the expression of antioxidant and detoxifying enzymes. Moreover, a crucial
role … tissue, chondrocytes proliferate and form an extracellular matrix (ECM) resulting in a …

… a tripeptide known for its active antioxidant role [30]. The synthesis … matrix production with
an anti-inflammatory role [35]. … Again, the lack of long-term studies evaluating these antioxidant …

… cytokines and matrix … expression of antioxidant enzymes (superoxide dismutase-2 (SOD-2),
catalase (CAT), peroxiredoxin 3 and 5 (Prx 3 and 5) and thioredoxin (TRX)), was associated …

… and concentration of nonenzymatic antioxidants are also … the secretory function of salivary
glands, expressed as reduced… but also hypertrophy of the extracellular matrix (ECM). Under …

… and facilitating early prevention, diagnosis and treatment. To … their important roles in smooth
muscle cell migration and matrix … curative role of antioxidants in treating VC and VC-related …

… an antioxidative stress role, evaluated by increased expression of eNOS and vascular endothelial
growth factor-1 (VEGFR1) and by decreased expression of matrix … in the diagnosis and …

… , apoptosis and gene expression through interaction with transcription factors. Moreover, …
inhibition of matrix metalloproteinase 9 (MMP9) and in restoring the endothelial function has …

… associated with cancer induction [153]. Moreover, Nrf2 plays an important role in regulating
the expression of antioxidant … which are involved in the remodeling of the extracellular matrix, …

… the anti-inflammatory and antioxidant properties of various … has become an important diagnostic
and prognostic factor and is a … (CTGF) and osteopontin, as well as in extracellular matrix …